Acriflavine Impurities

It is effective against a wide range of malignancies, including osteosarcoma, breast, brain, lung, liver, colon, ovarian, and pancreatic cancers, as well as leukemia.

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Parent Drug Name Name of Impurity Catalogue No.
Aciflavine Acriflavine HCl (Mixture of Acriflavinium Chloride and Proflavine HCl) VE0012019View CAS 65589-70-0
Acriflavine Proflavine Hemisulfate VL5360002View CAS 3237-53-4

Acriflavine Related Compound

It is currently mostly used to treat parasitic infections as a topical antiseptic. also used to cure wounds with infections and clean the skin. It has the potential to be utilized as a fungicide.

References

  • Kawai, Mako, and Junichi Yamagishi. Mechanisms of Action of Acriflavine: Electron Microscopic Study of Cell Wall Changes Induced inStaphylococcus Aureusby Acriflavine. no. 9, Sept. 2009, pp. 481–86, https://doi.org/10.1111/j.1348-0421.2009.00151.x. Accessed 13 June 2023.
  • ‌Gabriel, Iwona. “Acridines” as New Horizons in Antifungal Treatment. no. 7, Mar. 2020, pp. 1480–80, https://doi.org/10.3390/molecules25071480. Accessed 13 June 2023.
  • ‌“Acriflavine: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2023, go.drugbank.com/drugs/DB13373. Accessed 13 June 2023.

FAQ

What is the mechanism of action of acriflavine in Staphylococcus aureus cell wall modifications?

In S. aureus, acriflavine treatment increases cell wall thickness in both cross and peripheral walls. These findings imply that the synthesis of the cross and peripheral walls is governed by two distinct mechanisms. It is possible that acriflavine works on two distinct targets that govern these processes. Acriflavine’s method of action may include targeting proteins involved in cell wall production.

Is Acriflavine an antifungal?

Acriflavine is an antiseptic and efficient parasitic infection treatment. It can be used as a fungicide. had been previously established that the drug was capable of inducing mutations in yeast. Saccharomyces cerevisiae and Trypanosomatidae kinetoplast loss.

What is acriflavine used for?

Acriflavine is a topical antiseptic used to heal wounds with infections and clean the skin. It is an effective antibacterial medicine. It is effective in treating, mouth, as well as oral fungus, ulcers, and germs.

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3237-53-4: Proflavine Hemisulfate

3237-53-4: Proflavine Hemisulfate
Catalogue No.

VL5360002

CAS No.

3237-53-4

Molecular Formula

C13H13N3O4S

Molecular Weight

307.33 g/mol

Parent drug

Acriflavine

IUPAC Name

acridine-3, 6-diamine;sulfuric acid

Synonyms

N/A

References

Prieto, Sandra P., et al. “Proflavine Hemisulfate as a Fluorescent Contrast Agent for Point-of-Care Cytology.” PLOS ONE, edited by Anthony W.I. Lo, vol. 10, no. 5, May 2015, p. e0125598, https://doi.org/10.1371/journal.pone.0125598.

Status

In-stock

ListName

Proflavine Hemisulfate

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Exclusively Supplied by Veeprho

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