Adefovir Impurities

Adefovir is used to treat chronic (long-term) hepatitis B infection (viral-caused liver swelling).

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Adefovir Related Compound

Adefovir belongs to the class of drugs known as nucleotide analogs. It works by lowering the level of the hepatitis B virus (HBV) in the body.

References

  • “Adefovir: MedlinePlus Drug Information.” Medlineplus.gov, 2018, medlineplus.gov/drug info/meds/a605024.html#:~:text=Adefovir%20is%20in%20a%20class,(HBV)%20in%20the%20body. Accessed 17 June 2023.
  • ‌“Adefovir Dipivoxil: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2016, go.drugbank.com/drugs/DB00718. Accessed 17 June 2023.
  • ‌PubChem. “Adefovir.” @Pubchem, PubChem, 2023, pubchem.ncbi.nlm.nih.gov/compound/Adefovir. Accessed 17 June 2023.

FAQ

Adefovir belongs to which class of drug?

Adefovir belongs to a group of drugs known as nucleotide analogs. It works by lowering the level of the hepatitis B virus (HBV) in the body.

What is the mechanism of action of adefovir?

By competing with the natural substrate deoxyadenosine triphosphate and inducing DNA chain termination following inclusion into viral DNA, adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase).

What is the clinical use of adefovir?

Adefovir, a phosphonic acid that belongs to the methylphosphonic acid group, is used to treat chronic hepatitis B virus infection. It is an inhibitor of HIV-1 reverse transcriptase. It acts as an HIV-1 reverse transcriptase inhibitor, drug metabolite, antiviral agent, nephrotoxic agent, and DNA synthesis inhibitor.