|Parent Drug Name||Name of Impurity||Catalogue No.|
|Alendronate||Alendronate EP Impurity B||VE007830||View CAS 14265-44-2|
|Alendronate||Alendronate EP Impurity C||VE007834||View CAS 14901-63-4|
|Alendronate||Alendronate Impurity 1||VL5730006||View|
Alendronate Related Compound
Alendronate is a drug used to treat and prevent osteoporosis.
- Alendronate (Oral Route) Precautions – Mayo Clinic.” Mayoclinic.org, 2023, www.mayoclinic.org/drugs-supplements/alendronate-oral-route/precautions/drg-20061571?p=1#:~:text=Alendronate%20is%20used%20to%20prevent,(cortisone%2Dlike%20medicine). Accessed 13 Feb. 2023.
- Azuma, Y., et al. “Effects of Alendronate on Plasma Calcium Levels, Urinary Calcium Excretion, and Bone Resorption Markers in Normal Rats: Comparison with Elcatonin, Synthetic Eel Calcitonin.” Endocrinology, vol. 137, no. 6, June 1996, pp. 2586–92, https://doi.org/10.1210/endo.137.6.8641213. Accessed 13 Feb. 2023.
- Alendronate: MedlinePlus Drug Information.” Medlineplus.gov, 2020, medlineplus.gov/druginfo/meds/a601011.html#:~:text=Alendronate%20is%20in%20a%20class,increasing%20bone%20density%20(thickness). Accessed 13 Feb. 2023.
What is the therapeutic use of alendronate?
Alendronate is used to prevent and treat osteoporosis (bone weakening) in women following menopause. This medication may also be used to enhance bone mass in males who have osteoporosis, as well as to prevent and treat osteoporosis induced by long-term corticosteroid usage in both men and women (cortisone-like medicine).
Does alendronate reduce calcium?
According to the results, alendronate lowers plasma Ca predominantly by limiting bone resorption, whereas elcatonin lowers plasma Ca by blocking bone resorption and increasing calcium excretion.
Alendronate belongs to what drug class?
Alendronate belongs to the class of drugs known as bisphosphonates. It prevents bone breakdown and increases bone density (thickness).