Alendronic Acid Impurities

Alendronic acid is a bisphosphonate, which is a type of medication.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Alendronic Acid Alendronic Acid

Alendronic Acid

VL5730001 66376-36-1
Alendronic Acid Dimeric Anhydride Alendronic Acid

Alendronic Acid Dimeric Anhydride

VL5730005 165043-20-9
Alendronic Acid Impurity 2 Alendronic Acid

Alendronic Acid Impurity 2

VL5730004 73858-59-0
Alendronic Acid Related Impurity 2 Alendronic Acid

Alendronic Acid Related Impurity 2

VL5730007 165043-19-6
Alendronic Acid Sodium Salt Alendronic Acid

Alendronic Acid Sodium Salt

VE0012082 129318-43-0
Alendronic Acid-D6 Alendronic Acid

Alendronic Acid-D6

DVE00129 1035437-39-8
1-(dimethoxyphosphoryl)-4-(1,3-dioxoisoindolin-2-yl)butyl dimethyl phosphate Alendronic Acid

1-(dimethoxyphosphoryl)-4-(1,3-dioxoisoindolin-2-yl)butyl dimethyl phosphate

VE0011101 N/A

Alendronic Acid Related Compound

Bisphosphonates are suggested because they help your bones maintain their strength. If or have a risk of developing osteoporosis, using alendronic acid can assist.

References

  • “Alendronic Acid: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2023, go.drugbank.com/drugs/DB00630. Accessed 28 June 2023.
  • “Zoledronic Acid Injection: MedlinePlus Drug Information.” Medlineplus.gov, 2023, medlineplus.gov/druginfo/meds/a605023.html#:~:text=Zoledronic%20acid%20is%20in%20a,the%20bones%20into%20the%20blood. Accessed 28 June 2023.

FAQ

What is the indication of alendronic acid?

Alendronic acid is used to treat and prevent osteoporosis in men and postmenopausal women, as well as to treat glucocorticoid-induced osteoporosis and Paget’s disease of bone.

What is the mechanism of action of alendronic acid?

Even so, although pyrophosphate inhibits both osteoclastic bone resorption and the mineralization of freshly generated bone by osteoblasts at pharmacologically feasible dosages, alendronate solely inhibits bone resorption with no impact on mineralization.

How does alendronic acid benefit the bones?

It works by reducing bone disintegration, increasing bone density (thickness), and lowering the amount of calcium released into the blood from the bones.