Allopurinol Impurities

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Allopurinol Related Compound

Allopurinol is used to treat gout (a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints and causes sudden attacks of redness, swelling, pain, and heat in one or more joints.

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FAQ’s

What is the therapeutic effect of allopurinol?

Allopurinol is a medication used to prevent or reduce elevated uric acid levels in the blood. It is also used to prevent or reduce high uric acid levels generated by cancer medications or in individuals suffering from kidney stones. Gout or gouty arthritis can be caused by a high uric acid level (joint pain and inflammation).

What is allopurinol's mechanism of action?

Both allopurinol and oxypurinol block xanthine oxidase, a purine catabolism enzyme that transforms hypoxanthine to xanthine and thereafter to uric acid.

Can allopurinol cause an increase in blood pressure?

Allopurinol is related with a slight but considerable decrease in blood pressure. This action has the potential to be used to help manage blood pressure in hypertensive individuals with hyperuricemia.