Amodiaquine Impurities

Amodiaquine is an aminoquinoline that is used to treat malaria.

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Parent Drug Name Name of Impurity Catalogue No.
Amodiaquine Amodiaquine Diethylamino Acetamide Impurity VL6380008View CAS 121-78-8
Amodiaquine Amodiaquine Dihydrochloride Dihydrate VL6380010View CAS 6398-98-7
Amodiaquine Amodiaquine Impurity 3 VE007968View CAS 3011-34-5
Amodiaquine Amodiaquine Impurity 4 VE007969View CAS 399-96-2
Amodiaquine Amodiaquine Impurity 5 VE007970View CAS 71130-60-4
Amodiaquine Amodiaquine Impurity 6 VE007971View CAS 79352-72-0
Amodiaquine Amodiaquine Impurity 7 VE007973View CAS 37672-04-1
Amodiaquine Amodiaquine Impurity B VL6380005View CAS 103-90-2
Amodiaquine Amodiaquine Inhouse Impurity A VE007966View CAS 81080-09-3
Amodiaquine Amodiaquine Inhouse Impurity B VE007967View CAS 81099-86-7
Amodiaquine Amodiaquine N-Desethyl HCl VL6380011View CAS 1246819-11-3
Amodiaquine Amodiaquine N-Oxide VE0012217View CAS 102391-07-1
Amodiaquine Amodiaquine-D10 DVE0035View CAS 1189449-70-4
Amodiaquine N-Desethyl Amodiaquine Dihydrochloride Vl6380001View CAS 79049-30-2
Amodiaquine N-Desethyl Amodiaquine-D5 Di(HCl) DVE0034View CAS 1216894-33-5

Amodiaquine Related Compound

Amodiaquine has been related to severe episodes of acute hepatitis, which can be deadly, hence it is only suggested for use as a therapy and not for malaria prevention.

References

FAQ

What is the mechanism of action of amodiaquine?

It is hypothesized to limit heme polymerase activity, like other quinoline derivatives. As a result, free heme accumulates, which is poisonous to the parasites. The medicine attaches to the free heme and prevents the parasite from converting to a less harmful form. This hazardous drug-heme combination affects membrane function.

Is amodiaquine a schizonticide for the blood?

Amodiaquine is quinoline-based blood schizonticidal medicine that kills malaria parasites, primarily P. falciparum.

What are the uses of amodiaquine?

Amodiaquine (ADQ) is a drug used to treat uncomplicated malaria, especially Plasmodium falciparum malaria. It is advised that it be taken in conjunction with artesunate to lessen the chance of resistance. Malaria prevention is not commonly suggested because of the possibility of uncommon but significant adverse effects.

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102391-07-1: Amodiaquine N-Oxide

102391-07-1: Amodiaquine N-Oxide
Catalogue No.

VE0012217

CAS No.

102391-07-1

Molecular Formula

C20H22ClN3O2

Molecular Weight

371.87 g/mol

Parent drug

Amodiaquine

IUPAC Name

N-(5-((7-chloroquinolin-4-yl)amino)-2-hydroxybenzyl)-N-ethylethanamine oxide

Synonyms

N/A

References

Status

In-stock

ListName

Amodiaquine N-Oxide

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