Anthraquinone Impurities

Anthraquinones are bioactive natural compounds, some of which are active ingredients in pharmaceuticals, particularly Chinese remedies.

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Parent Drug Name Name of Impurity Catalogue No.
Anthraquinone Anthraquinone 1, 4, 5-Trihydroxyanthraquinone VL6700005View CAS 2961-04-8
Anthraquinone Anthraquinone 1, 5-Dihydroxyanthraquinone VL6700004View CAS 117-12-4

Anthraquinone Related Compound

These compounds have purgative, anti-inflammation, immunoregulation, antihyperlipidemia, and anticancer properties.

References

FAQ

What is the mechanism of action of Anthraquinone in laxatives?

Two distinct mechanisms of action have been proposed: (1) an effect on large intestine motility, resulting in accelerated colonic transit and decreased fluid absorption, and (2) an effect on secretory processes, resulting in increased fluid absorption. One major biological target is the blockage of Cl channels across colon cells, which contributes to the laxative effect [2]. Furthermore, those 1,8-dihydroxyanthrones/anthraquinones with an extra phenolic hydroxyl group block the Na+/K+-ATPase pump.

What is the function of anthraquinone?

Apart from its usage as colorants, anthraquinone derivatives have been utilized in medicine for centuries, for example, as laxatives, antibacterial and anti-inflammatory medicines. Current therapeutic indications include constipation, arthritis, multiple sclerosis, and malignancy.

Is anthraquinone an antioxidant?

The anthraquinones, which also have antioxidant activity, had essentially no reducing power, implying that, with the exception of anthrone and alizarin, the reducing power of other anthraquinonoids cannot be considered as contributing to their antioxidative action.

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117-12-4: Anthraquinone 1,5-Dihydroxyanthraquinone

117-12-4: Anthraquinone 1,5-Dihydroxyanthraquinone
Catalogue No.

VL6700004

CAS No.

117-12-4

Molecular Formula

C14H8O4

Molecular Weight

240.21 g/mol

Parent drug

Anthraquinone

IUPAC Name

1, 5-dihydroxyanthracene-9, 10-dione

Synonyms

N/A

References

Van Benthem, Mark H., and G. D. Gillispie. “Intramolecular Hydrogen Bonding. 4. Dual Fluorescence and Excited-State Proton Transfer in 1, 5-Dihydroxyanthraquinone.” The Journal of Physical Chemistry, vol. 88, no. 14, July 1984, pp. 2954–2960, 10.1021/j150658a008. Accessed 26 Jan. 2022.

Status

In-stock

ListName

Anthraquinone 1, 5-Dihydroxyanthraquinone

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