| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Atazanavir | Atazanavir Benzylidenehydrazine Carbamate | VE0012404 | View |
| Atazanavir | Atazanavir EP Impurity B | VL2230001 | View CAS 127406-56-8 |
| Atazanavir | Atazanavir EP Impurity C | VE0012399 | View CAS 1192224-24-0 |
| Atazanavir | Atazanavir EP Impurity D | VL2230003 | View |
| Atazanavir | Atazanavir EP Impurity H | VL2230009 | View |
| Atazanavir | Atazanavir EP Impurity J | VE0012407 | View CAS 198904-86-8 |
| Atazanavir | Atazanavir Hydrazine Analog (3HCl Salt) | VE0012417 | View CAS 198904-87-9 |
| Atazanavir | Atazanavir Impurity 1 | VL2230005 | View CAS 1292296-09-3 |
| Atazanavir | Atazanavir Impurity 10 | VE0012413 | View |
| Atazanavir | Atazanavir Impurity 2 | VL2230006 | View |
| Atazanavir | Atazanavir Impurity 3 | VL2230007 | View |
| Atazanavir | Atazanavir Impurity 4 | VE0012410 | View |
| Atazanavir | Atazanavir Impurity 6 | VE0012414 | View CAS 1006868-81-0 |
| Atazanavir | Atazanavir Impurity 7 | VE0012415 | View CAS 1192224-26-2 |
| Atazanavir | Atazanavir Impurity 8 | VE0012416 | View CAS 1028634-76-5 |
| Atazanavir Impurity 9 | Atazanavir Impurity 9 | VE0012412 | View |
| Atazanavir | Atazanavir Pyridinyl Benzoic Acid Impurity | VL2230010 | View CAS 4385-62-0 |
| Atazanavir | Atazanavir R, S, S, R-Diastereomer | VE0012402 | View CAS 1292296-11-7 |
| Atazanavir | Atazanavir R, S, S, S-Diastereomer | VE0012400 | View CAS 1332981-14-2 |
| Atazanavir | Atazanavir S, S, R, S-Diastereomer | VE0012403 | View CAS 1292296-10-6 |
| Atazanavir | Atazanavir S, S, S, R-Diastereomer | VE0012401 | View CAS 1332981-16-4 |
| Atazanavir | Atazanavir-D6 | DVE00167 | View CAS 1092540-50-5 |
| Atazanavir | (E)-1-(4-(Pyridin-2-yl)benzylidene)hydrazine | VE007002 | View CAS 257907-05-4 |
Atazanavir Related Compound
It belongs to the protease inhibitor class. These medications treat human immunodeficiency virus (HIV) infection by blocking a protein required for HIV replication.
References
- Achenbach, Chad J., et al. Atazanavir/Ritonavir-Based Combination Antiretroviral Therapy for Treatment of HIV-1 Infection in Adults. no. 2, Feb. 2011, pp. 157–77, https://doi.org/10.2217/fvl.10.89. Accessed 30 July 2023.
- “Atazanavir: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2020, go.drugbank.com/drugs/DB01072. Accessed 30 July 2023.
FAQ
What is the pharmacological action of atazanavir?
Atazanavir binds to the protease active site and reduces the enzyme’s activity. This inhibits viral polyprotein cleavage, resulting in the generation of immature non-infectious viral particles. Protease inhibitors are generally often used with at least two additional anti-HIV medications.
To which class does Atazanavir belong?
Atazanavir belongs to the class of drugs known as protease inhibitors. It works by lowering the level of HIV in the blood.
What is the mechanism of action of atazanavir?
Atazanavir is an aza peptide HIV-1 PI that suppresses the production of mature virions in HIV-1-infected cells by inhibiting viral Gag and Gag-Pol polyprotein processing.
