Azahypoxanthine Impurities

2-Azahypoxanthine (AHX) was discovered in the growing broth of Lepista sordida, a fairy ring-forming fungus.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
2-Azahypoxanthine Sodium Salt Azahypoxanthine

2-Azahypoxanthine Sodium Salt

VE006270 1797817-35-6

Azahypoxanthine Related Compound

The findings corroborate the hypothesis that (aza hypoxanthine) AHX was synthesized from (5-aminoimidazole-4-carboxamide ribonucleotide) AICAR and that AHX biosynthesis was transcriptionally regulated by AICAR, implying the establishment of a new purine metabolic pathway in L. sordid. And AHX has beneficial effects on plant growth. Also used as a growth stimulator, whereas is a nonspecific cell cycle antineoplastic drug.

References

  • “Biosynthesis of the Fairy Chemicals, 2-Azahypoxanthine and Imidazole-4-Carboxamide, in the Fairy Ring-Forming Fungus Lepista Sordida.” Journal of Natural Products, 2020, pubs.acs.org/doi/10.1021/acs.jnatprod.0c00394. Accessed 6 Aug. 2023.
  • “2-Azahypoxanthine Sodium Salt.” Trc-Canada.com, 2018, www.trc-canada.com/product-detail/?A800100. Accessed 6 Aug. 2023.
  • Suzuki, Tomohiro, et al. The Biosynthetic Pathway of 2-Azahypoxanthine in Fairy-Ring Forming Fungus. no. 1, Dec. 2016, https://doi.org/10.1038/srep39087. Accessed 6 Aug. 2023.

FAQ

Is Azahypoxanthine used to treat cancer?

Is a nonspecific cell cycle antineoplastic drug that acts as an alkylating agent following activation in the liver. The medication is used to treat metastatic malignant melanoma. It is also administered to people suffering from Hodgkin’s disease.

What class of drug does Azahypoxanthine belong to?

Among the photodegradation products of dacarbazine, it is a causative agent of vascular discomfort.

What is the use of Azahypoxanthine?

AHX is a natural substance generated by a fungus that promotes grass growth. And AHX has beneficial effects on plant growth. Also used as a growth stimulator.