| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Azathioprine | Azathioprine EP Impurity A | VL4730001 | View CAS 4531-54-8 |
| Azathioprine | Azathioprine EP Impurity B | VE008748 | View CAS 157930-13-7 |
| Azathioprine | Azathioprine EP Impurity C | VL4730002 | View CAS 4897-25-0 |
| Azathioprine | Azathioprine EP Impurity D | VL4730006 | View CAS 6339-54-4 |
| Azathioprine | Azathioprine EP Impurity E | VL4730005 | View CAS 73703-74-9 |
| Azathioprine | Azathioprine EP Impurity E Sodium Salt | VE0012541 | View CAS 35681-68-6 |
| Azathioprine | Azathioprine EP Impurity F | VL4730008 | View CAS 68-94-0 |
| Azathioprine | Azathioprine EP Impurity G | VL4730003 | View CAS 5581-52-2 |
| Azathioprine | Azathioprine EPCRS (A1500000) | PVE00184 | View CAS 446-86-6 |
| Azathioprine | Azathioprine Impurity 1 | VE0010939 | View |
| Azathioprine | Azathioprine Impurity 19 | VE0012525 | View CAS 108372-41-4 |
Azathioprine Related Compound
Also used to treat Autoimmune hepatitis (AIH).
References
- Azathioprine Information for Patients and Parents Medicines Information. www.ouh.nhs.uk/patient-guide/leaflets/files/100722paedazathioprine.pdf.
- “UpToDate.” Uptodate.com, 2023, www.uptodate.com/contents/pharmacology-and-side-effects-of-azathioprine-when-used-in-rheumatic-diseases#:~:text=Azathioprine%20(AZA)%20is%20an%20immunosuppressive,RNA)%2C%20and%20protein%20synthesis. Accessed 6 Aug. 2023.
FAQ
What is the mechanism of action of Azathioprine?
Azathioprine (AZA) is an immunosuppressive drug that inhibits deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein production by acting as an antagonist of purine metabolism.
Is Azathioprine used to treat Autoimmune hepatitis (AIH)?
Autoimmune hepatitis (AIH) is a chronic liver disease that generally lasts a lifetime. Autoimmune disease occurs when your immune system (your body’s protection against sickness) destroys your own cells. Azathioprine is a medication that aids in the treatment of this illness. To cure inflammation, it inhibits the body’s immune system.
Is azathioprine a steroid?
Azathioprine is sometimes known as a “steroid-sparing agent” or “immunomodulator.” It permits the steroid dose to be reduced and finally eliminated. Azathioprine is also used to treat patients with organ transplants, rheumatoid arthritis, and psoriasis.
