Parent Drug Name | Name of Impurity | Catalogue No. | |
---|---|---|---|
Bepotastine | Bepotastine Desbutyrate Impurity (Tartrate) | VE006632 | View CAS 210095-58-2 |
Bepotastine | Bepotastine Deschloro Impurity | VE008616 | View |
Bepotastine | Bepotastine Ethyl Ester | VE006604 | View CAS 190730-39-3 |
Bepotastine | Bepotastine Ethyl Ester (Besilate Salt) | VE008614 | View |
Bepotastine | Bepotastine Isopropyl Ester | VE008600 | View CAS 1807607-93-7 |
Bepotastine | Bepotastine Methyl Ester (Besilate Salt) | VE008613 | View |
Bepotastine | Bepotastine N-Butyl Ester | VE008601 | View CAS 1807606-59-2 |
Bepotastine | Bepotastine N-Oxide Impurity | VE008856 | View |
Bepotastine | Bepotastine Piperidine N-Oxide | VE009215 | View |
Bepotastine | rac-Bepotastine-D6 | DVE00215 | View |
Bepotastine | (R)-Bepotastine Besylate | VE008604 | View CAS 190730-42-8 |
Bepotastine Related Compound
It works by inhibiting the activity of histamine, a chemical in the body that produces allergic reactions. It is an H1 antihistamine that inhibits mast cell histamine release.
References
- “Bepotastine Ophthalmic: MedlinePlus Drug Information.” Medlineplus.gov, 2016, medlineplus.gov/druginfo/meds/a610012.html#:~:text=Bepotastine%20is%20in%20a%20class,body%20that%20causes%20allergic%20symptoms. Accessed 24 Aug. 2023.
- Wingard, Jeremy B., and Francis S. Mah. “Critical Appraisal of Bepotastine in the Treatment of Ocular Itching Associated with Allergic Conjunctivitis.” Clinical Ophthalmology, Dove Medical Press, Feb. 2011, pp. 201–1, https://doi.org/10.2147/opth.s8665. Accessed 24 Aug. 2023.
FAQ
What is the mechanism of action of bepotastine?
Bepotastine is available in the form of an ocular solution and an oral tablet. It is a direct H1-receptor antagonist that prevents mast cell histamine release. In healthy people, the ocular formulation showed little systemic absorption, ranging between 1 and 1.5%.
What generation is bepotastine?
Oral bepotastine is a histamine H(1) receptor antagonist of the second generation that also lowers various allergic inflammatory processes.
What is bepotastine in dermatology?
In vivo, bepotastine suppresses histamine-induced wheal and flare response. The active enantiomer of cetirizine is levocetirizine. It is a second-generation H1 receptor antagonist that is both powerful and selective, and it is used to treat allergic rhinitis and urticaria.