Bepotastine Impurities

Bepotastine belongs to the antihistamine drug class.

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Parent Drug Name Name of Impurity Catalogue No.
Bepotastine Bepotastine Desbutyrate Impurity (Tartrate) VE006632View CAS 210095-58-2
Bepotastine Bepotastine Deschloro Impurity VE008616View
Bepotastine Bepotastine Ethyl Ester VE006604View CAS 190730-39-3
Bepotastine Bepotastine Ethyl Ester (Besilate Salt) VE008614View
Bepotastine Bepotastine Isopropyl Ester VE008600View CAS 1807607-93-7
Bepotastine Bepotastine Methyl Ester (Besilate Salt) VE008613View
Bepotastine Bepotastine N-Butyl Ester VE008601View CAS 1807606-59-2
Bepotastine Bepotastine N-Oxide Impurity VE008856View
Bepotastine Bepotastine Piperidine N-Oxide VE009215View
Bepotastine rac-Bepotastine-D6 DVE00215View
Bepotastine (R)-Bepotastine Besylate VE008604View CAS 190730-42-8

Bepotastine Related Compound

It works by inhibiting the activity of histamine, a chemical in the body that produces allergic reactions. It is an H1 antihistamine that inhibits mast cell histamine release.

References

  • “Bepotastine Ophthalmic: MedlinePlus Drug Information.” Medlineplus.gov, 2016, medlineplus.gov/druginfo/meds/a610012.html#:~:text=Bepotastine%20is%20in%20a%20class,body%20that%20causes%20allergic%20symptoms. Accessed 24 Aug. 2023.
  • Wingard, Jeremy B., and Francis S. Mah. “Critical Appraisal of Bepotastine in the Treatment of Ocular Itching Associated with Allergic Conjunctivitis.” Clinical Ophthalmology, Dove Medical Press, Feb. 2011, pp. 201–1, https://doi.org/10.2147/opth.s8665. Accessed 24 Aug. 2023.

FAQ

What is the mechanism of action of bepotastine?

Bepotastine is available in the form of an ocular solution and an oral tablet. It is a direct H1-receptor antagonist that prevents mast cell histamine release. In healthy people, the ocular formulation showed little systemic absorption, ranging between 1 and 1.5%.

What generation is bepotastine?

Oral bepotastine is a histamine H(1) receptor antagonist of the second generation that also lowers various allergic inflammatory processes.

What is bepotastine in dermatology?

In vivo, bepotastine suppresses histamine-induced wheal and flare response. The active enantiomer of cetirizine is levocetirizine. It is a second-generation H1 receptor antagonist that is both powerful and selective, and it is used to treat allergic rhinitis and urticaria.

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1807606-59-2: Bepotastine N-Butyl Ester

1807606-59-2: Bepotastine N-Butyl Ester
Catalogue No.

VE008601
CAS No.

1807606-59-2
Molecular Formula

C25H33ClN2O3
Molecular Weight

444.99 g/mol
Parent drug

Bepotastine
IUPAC Name

(S)-Butyl 4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoate
Synonyms

N/A
References

Cavet, M. E., Gomes, P. J., Carr, W. W., & Williams, J. I. (2018). Bepotastine besilate ophthalmic solution 1.5% for alleviating nasal symptoms in patients with allergic conjunctivitis. Journal of Asthma and Allergy, Volume 11, 29–39. https://doi.org/10.2147/jaa.s160687
Status

In-stock
ListName

Bepotastine N-Butyl Ester
Exclusively Supplied by Veeprho

Exclusively Supplied by Veeprho

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