|Parent Drug Name||Name of Impurity||Catalogue No.|
|Bepotastine||Bepotastine Desbutyrate Impurity (Tartrate)||VE006632||View CAS 210095-58-2|
|Bepotastine||Bepotastine Deschloro Impurity||VE008616||View|
|Bepotastine||Bepotastine Ethyl Ester||VE006604||View CAS 190730-39-3|
|Bepotastine||Bepotastine Ethyl Ester (Besilate Salt)||VE008614||View|
|Bepotastine||Bepotastine Isopropyl Ester||VE008600||View CAS 1807607-93-7|
|Bepotastine||Bepotastine Methyl Ester (Besilate Salt)||VE008613||View|
|Bepotastine||Bepotastine N-Butyl Ester||VE008601||View CAS 1807606-59-2|
|Bepotastine||Bepotastine N-Oxide Impurity||VE008856||View|
|Bepotastine||Bepotastine Piperidine N-Oxide||VE009215||View|
|Bepotastine||(R)-Bepotastine Besylate||VE008604||View CAS 190730-42-8|
Bepotastine Related Compound
It works by inhibiting the activity of histamine, a chemical in the body that produces allergic reactions. It is an H1 antihistamine that inhibits mast cell histamine release.
- “Bepotastine Ophthalmic: MedlinePlus Drug Information.” Medlineplus.gov, 2016, medlineplus.gov/druginfo/meds/a610012.html#:~:text=Bepotastine%20is%20in%20a%20class,body%20that%20causes%20allergic%20symptoms. Accessed 24 Aug. 2023.
- Wingard, Jeremy B., and Francis S. Mah. “Critical Appraisal of Bepotastine in the Treatment of Ocular Itching Associated with Allergic Conjunctivitis.” Clinical Ophthalmology, Dove Medical Press, Feb. 2011, pp. 201–1, https://doi.org/10.2147/opth.s8665. Accessed 24 Aug. 2023.
What is the mechanism of action of bepotastine?
Bepotastine is available in the form of an ocular solution and an oral tablet. It is a direct H1-receptor antagonist that prevents mast cell histamine release. In healthy people, the ocular formulation showed little systemic absorption, ranging between 1 and 1.5%.
What generation is bepotastine?
Oral bepotastine is a histamine H(1) receptor antagonist of the second generation that also lowers various allergic inflammatory processes.
What is bepotastine in dermatology?
In vivo, bepotastine suppresses histamine-induced wheal and flare response. The active enantiomer of cetirizine is levocetirizine. It is a second-generation H1 receptor antagonist that is both powerful and selective, and it is used to treat allergic rhinitis and urticaria.