Bepotastine Impurities

Bepotastine belongs to the antihistamine drug class.

Show
per page
Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Bepotastine Desbutyrate Impurity (Tartrate) Bepotastine

Bepotastine Desbutyrate Impurity (Tartrate)

VE006632 210095-58-2
Bepotastine Deschloro Impurity Bepotastine

Bepotastine Deschloro Impurity

VE008616 N/A
Bepotastine Ethyl Ester Bepotastine

Bepotastine Ethyl Ester

VE006604 190730-39-3
Bepotastine Ethyl Ester (Besilate Salt) Bepotastine

Bepotastine Ethyl Ester (Besilate Salt)

VE008614 N/A
Bepotastine Isopropyl Ester Bepotastine

Bepotastine Isopropyl Ester

VE008600 1807607-93-7
Bepotastine Methyl Ester (Besilate Salt) Bepotastine

Bepotastine Methyl Ester (Besilate Salt)

VE008613 N/A
Bepotastine N-Butyl Ester Bepotastine

Bepotastine N-Butyl Ester

VE008601 1807606-59-2
Bepotastine N-Oxide Impurity Bepotastine

Bepotastine N-Oxide Impurity

VE008856 N/A
Bepotastine Piperidine N-Oxide Bepotastine

Bepotastine Piperidine N-Oxide

VE009215 N/A
rac-Bepotastine-D6 Bepotastine

rac-Bepotastine-D6

DVE00215 N/A
(R)-Bepotastine Besylate Bepotastine

(R)-Bepotastine Besylate

VE008604 190730-42-8

Bepotastine Related Compound

It works by inhibiting the activity of histamine, a chemical in the body that produces allergic reactions. It is an H1 antihistamine that inhibits mast cell histamine release.

References

  • “Bepotastine Ophthalmic: MedlinePlus Drug Information.” Medlineplus.gov, 2016, medlineplus.gov/druginfo/meds/a610012.html#:~:text=Bepotastine%20is%20in%20a%20class,body%20that%20causes%20allergic%20symptoms. Accessed 24 Aug. 2023.
  • Wingard, Jeremy B., and Francis S. Mah. “Critical Appraisal of Bepotastine in the Treatment of Ocular Itching Associated with Allergic Conjunctivitis.” Clinical Ophthalmology, Dove Medical Press, Feb. 2011, pp. 201–1, https://doi.org/10.2147/opth.s8665. Accessed 24 Aug. 2023.

FAQ

What is the mechanism of action of bepotastine?

Bepotastine is available in the form of an ocular solution and an oral tablet. It is a direct H1-receptor antagonist that prevents mast cell histamine release. In healthy people, the ocular formulation showed little systemic absorption, ranging between 1 and 1.5%.

What generation is bepotastine?

Oral bepotastine is a histamine H(1) receptor antagonist of the second generation that also lowers various allergic inflammatory processes.

What is bepotastine in dermatology?

In vivo, bepotastine suppresses histamine-induced wheal and flare response. The active enantiomer of cetirizine is levocetirizine. It is a second-generation H1 receptor antagonist that is both powerful and selective, and it is used to treat allergic rhinitis and urticaria.