| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Bexarotene | Bexarotene Acyl Glucuronide | VE0012742 | View CAS 198700-33-3 |
| Bexarotene | Bexarotene Amide Impurity | VE006531 | View |
| Bexarotene | Bexarotene Impurity 11 | VE0012739 | View |
| Bexarotene | Bexarotene Impurity 12 | VE0012740 | View |
| Bexarotene | Bexarotene Impurity 8 | VE0012731 | View CAS 29641-87-0 |
| Bexarotene | Bexarotene Keto Acid Impurity | VE006530 | View CAS 153559-46-7 |
| Bexarotene | Bexarotene Ketone Methyl Ester Impurity | VE006533 | View CAS 153559-45-6 |
| Bexarotene | Bexarotene Methyl Ester Impurity | VE006534 | View CAS 153559-48-9 |
| Bexarotene | Bexarotene Tetrahydro Naphthalene Impurity | VE006532 | View CAS 6683-48-3 |
| Bexarotene | Bexarotene-D4 | DVE00227 | View |
| Bexarotene | 6-Hydroxy Bexarotene | VE0012741 | View |
| Bexarotene | 7-Oxo Bexarotene | VE0012743 | View CAS 368451-15-4 |
Bexarotene Related Compound
Bexarotene belongs to the retinoids class of medicines. It works by preventing cancer cell development.
References
- “Targretin (Bexarotene) Dosing, Indications, Interactions, Adverse Effects, and More.” Medscape.com, 13 Apr. 2023, reference.medscape.com/drug/targretin-bexarotene-342234#:~:text=Hypoglycemia%20has%20not%20been%20associated%20with%20bexarotene%20monotherapy.&text=siponimod%20and%20bexarotene%20both%20increase%20immunosuppressive%20effects%3B%20risk%20of%20infection. Accessed 25 Aug. 2023.
- “Bexarotene: MedlinePlus Drug Information.” Medlineplus.gov, 2023, medlineplus.gov/druginfo/meds/a608006.html#:~:text=Bexarotene%20is%20used%20to%20treat,the%20growth%20of%20cancer%20cells. Accessed 25 Aug. 2023.
- “Bexarotene | DermNet.” Dermnetnz.org, 2022, dermnetnz.org/topics/bexarotene#:~:text=Kaposi%20sarcoma-,Mechanism%20of%20action%20of%20bexarotene,growth%2C%20apoptosis%2C%20and%20differentiation. Accessed 25 Aug. 2023.
FAQ
What is the mechanism of action of bexarotene?
Bexarotene binds and activates RXRs, which are ligand-activated transcription factors that regulate gene expression. This affects cell proliferation, apoptosis, and differentiation.
What are the indications for bexarotene?
Bexarotene capsules are approved for the treatment of cutaneous symptoms of cutaneous T-cell lymphoma.
What class of drug is bexarotene?
Bexarotene belongs to the retinoids class of medicines. It works by preventing cancer cell development.
