Budesonide Impurities

Asthma-related symptoms such as chest tightness, coughing, wheezing, and trouble breathing are prevented by budesonide. Inflammatory bowel disease Crohn’s disease, which is mild to moderately active, is treated with budesonide.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Androstandionic Impurity Budesonide

Androstandionic Impurity

VE007477 85234-64-6
Budesonide (22R)-Isomer Budesonide

Budesonide (22R)-Isomer

VE007464 51372-29-3
Budesonide (22S)-Isomer Budesonide

Budesonide (22S)-Isomer

VE007465 51372-28-2
Budesonide 1,4,14-Triene Triol Impurity Budesonide

Budesonide 1,4,14-Triene Triol Impurity

VE007466 131918-72-4
Budesonide 17-Carboxylic Acid Impurity Budesonide

Budesonide 17-Carboxylic Acid Impurity

VL34013 192057-49-1
Budesonide 17, 21-Diacetyloxy Impurity Budesonide

Budesonide 17, 21-Diacetyloxy Impurity

VL34015 17652-24-3
Budesonide 21-Butyrate Impurity Budesonide

Budesonide 21-Butyrate Impurity

VL34014 2408495-96-3
Budesonide 21-Butyrate Impurity Budesonide

Budesonide 21-Butyrate Impurity

VE007467 N/A
Budesonide 6-alpha-Hydroxy Impurity Budesonide

Budesonide 6-alpha-Hydroxy Impurity

VE007468 577777-51-6
Budesonide 6-beta-Hydroxy Impurity Budesonide

Budesonide 6-beta-Hydroxy Impurity

VE007469 88411-77-2
Budesonide EP Impurity A Budesonide/prednisolone/Desonide

Budesonide EP Impurity A

VL34001 13951-70-7
Budesonide EP Impurity B Budesonide

Budesonide EP Impurity B

VL34002 1040085-98-0
Budesonide EP Impurity C Budesonide

Budesonide EP Impurity C

VL34003 1040085-99-1
Budesonide EP Impurity D Budesonide

Budesonide EP Impurity D

VL34008 85234-63-5
Budesonide EP Impurity E Budesonide

Budesonide EP Impurity E

VL34004 131918-64-4
Budesonide EP Impurity F Budesonide

Budesonide EP Impurity F

VL34005 638-94-8
Budesonide EP Impurity G Budesonide

Budesonide EP Impurity G

VL34009 137174-25-5
Budesonide EP Impurity H Budesonide

Budesonide EP Impurity H

VL34010 313474-58-7
Budesonide EP Impurity I Budesonide

Budesonide EP Impurity I

VL34006 113930-13-5
Budesonide EP Impurity J Budesonide

Budesonide EP Impurity J

VL34011 313474-59-8
Budesonide EP Impurity K Budesonide

Budesonide EP Impurity K

VL34012 51333-05-2
Budesonide EP Impurity L Budesonide

Budesonide EP Impurity L

VL34007 216453-74-6
Budesonide for System Suitability CRS (Y0001148) Budesonide

Budesonide for System Suitability CRS (Y0001148)

PVE00290 51333-22-3
Budesonide Impurity 1 (Mixture of Diastereomers) Budesonide

Budesonide Impurity 1 (Mixture of Diastereomers)

VE0012959
Budesonide Impurity 11 Budesonide

Budesonide Impurity 11

VE0012968 39672-76-9
Budesonide Impurity 13 Budesonide

Budesonide Impurity 13

VE0012969 N/A
Budesonide Impurity 16 Budesonide

Budesonide Impurity 16

VE0012970 77017-17-5
Budesonide Impurity 18 Budesonide

Budesonide Impurity 18

VE0012971 95943-95-6
Budesonide Impurity 22 Budesonide

Budesonide Impurity 22

VE0013070 N/A
Budesonide Impurity 24 Budesonide

Budesonide Impurity 24

VE0012976 601-38-7
Budesonide Impurity 4 Budesonide

Budesonide Impurity 4

VE0012962 N/A
Budesonide Impurity 6 Budesonide

Budesonide Impurity 6

VE007480 77017-20-0
Budesonide Impurity 7 Budesonide

Budesonide Impurity 7

VE0012967 3949-79-9
Budesonide Oxoacetic Acid Budesonide

Budesonide Oxoacetic Acid

VE007474 N/A
Budesonide Propionaldehyde Impurity Budesonide

Budesonide Propionaldehyde Impurity

VE007478 68293-09-4
Budesonide Related Compound 4 Budesonide

Budesonide Related Compound 4

VE007473 111088-90-5
Budesonide Sulfate Sodium Impurity Budesonide

Budesonide Sulfate Sodium Impurity

VE007475 N/A
Budesonide Sulfate Triethylamine Salt (Mixture of Diastereomers) Budesonide

Budesonide Sulfate Triethylamine Salt (Mixture of Diastereomers)

VE0012953 1436872-65-9
Budesonide-D6 Budesonide

Budesonide-D6

DVE001529 1134189-63-1
Budesonide-D8 (Mixture of Diastereomers) Budesonide

Budesonide-D8 (Mixture of Diastereomers)

DVE00259 1105542-94-6
(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one Budesonide

(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one

VE0013069 131918-73-5
1,2-Dihydrobudesonide-D8 Budesonide

1,2-Dihydrobudesonide-D8

DVE001530 N/A
1,4-Androstadien-11-beta-16-alpha-Diol-3,17-Dione Budesonide

1,4-Androstadien-11-beta-16-alpha-Diol-3,17-Dione

VE007976 910299-74-0
11?,16?,17?,21-Tetrahydroxypregna-1,4-diene-3,20-dione-D3 Budesonide

11?,16?,17?,21-Tetrahydroxypregna-1,4-diene-3,20-dione-D3

DVE001537 N/A
11?,16?,17?,21-Tetrahydroxypregna-1,4-diene-3,20-dione-D5 Budesonide

11?,16?,17?,21-Tetrahydroxypregna-1,4-diene-3,20-dione-D5

DVE001536 N/A
16α-Hydroxycortisol Impurity Budesonide

16α-Hydroxycortisol Impurity

VE007479 1171-81-9
17?-Des-(2-hydroxyacetyl)budesonide 17?-Carboxylic Acid-d8 Budesonide

17?-Des-(2-hydroxyacetyl)budesonide 17?-Carboxylic Acid-d8

DVE001531 N/A
21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione Budesonide

21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione

VE006999 3044-42-6
21-Acetyloxy Budesonide-D8 Budesonide

21-Acetyloxy Budesonide-D8

DVE001528 N/A
22R-6β-Hydroxy Budesonide Budesonide

22R-6β-Hydroxy Budesonide

VE007471 93861-52-0

Budesonide Related Compound

This medication reduces inflammation and illness symptoms by acting inside the intestines (bowels).

References

  • Kalola, Urvashi K., and Shashikanth Ambati. “Budesonide.” Nih.gov, StatPearls Publishing, 12 Mar. 2023, www.ncbi.nlm.nih.gov/books/NBK563201/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,HDCA2%20and%20CBP%20(HAT). Accessed 8 Sept. 2023.
  • “Budecort 1mg 2ml Packet of 5 Respules.” Pharmeasy.in, Pharmeasy, 2014, pharmeasy.in/online-medicine-order/budecort-1mg-packet-of-5-2ml-respules-38424. Accessed 8 Sept. 2023.
  • Bar-Meir, Simon, et al. “Budesonide versus Prednisone in the Treatment of Active Crohn’s Disease.” Gastroenterology, vol. 115, no. 4, Elsevier BV, Oct. 1998, pp. 835–40, https://doi.org/10.1016/s0016-5085(98)70254-9. Accessed 8 Sept. 2023.

FAQ

What is the use of budecort?

A powerful topical anti-inflammatory drug is budesonide. The budesonide-GR complicated, which interacts with both HDCA2 and CBP (HAT), translocates to the bronchial nucleus by binding to and activating glucocorticoid receptors (GR) in the cytoplasm of effector cells (such as bronchial cells).

What class of drug is budesonide?

The drug budesonide, which belongs to the corticosteroid class of drugs, reduces inflammation (swelling) in the digestive tract in individuals suffering from Crohn’s disease or in the kidney in persons with nephropathy.