Bupivacaine Impurities

Adults may use bupivacaine either by itself or in conjunction with epinephrine to produce local or regional anesthesia or analgesia during surgical, dental, and oral surgery operations, as well as for diagnostic and therapeutic treatments and obstetrical procedures.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Bupivacaine EP Impurity B Bupivacaine

Bupivacaine EP Impurity B

VE009447 15883-20-2
Bupivacaine EP Impurity B-D6 Bupivacaine

Bupivacaine EP Impurity B-D6

DVE00261 N/A
Bupivacaine EP Impurity D Bupivacaine

Bupivacaine EP Impurity D

VE0013101 1037184-07-8
Bupivacaine EP Impurity E Bupivacaine

Bupivacaine EP Impurity E

VE0013102 1330172-81-0
Bupivacaine Impurity 3 Bupivacaine

Bupivacaine Impurity 3

VE0013083 51989-48-1
Bupivacaine N-Oxide Bupivacaine

Bupivacaine N-Oxide

VE0012990 N/a
Bupivacaine N-Oxide (HCl Salt) Bupivacaine

Bupivacaine N-Oxide (HCl Salt)

VE0011299 1796927-05-3
Bupivacaine-D9 Bupivacaine

Bupivacaine-D9

DVE00262 474668-57-0
Lidocaine EP Impurity A-D6 Lidocaine; Bupivacaine; Ropivacaine

Lidocaine EP Impurity A-D6

DVE00775 N/A
1-butylpiperidine-2-carboxylic acid Bupivacaine

1-butylpiperidine-2-carboxylic acid

VE0012115 856838-98-7

Bupivacaine Related Compound

Additionally, buprenorphine significantly reduces inflammation-related pain by blocking the NF-B signaling pathway, as well as spinal microglia and astrocyte activation.

References

FAQ

What type of drug is bupivacaine?

The amide group of local anesthetics includes bupivacaine, a strong local anesthetic with distinctive properties. Local anesthetics are used for regional anesthesia, epidural anesthesia, spinal anesthesia, and local infiltration.

What is the action of the drug bupivacaine?

The recommended local anesthetic for caudal, epidural, and spinal anesthesia is bupivacaine, which is often used in clinical practice to treat both acute and long-term pain. Bupivacaine affects the activity of several additional channels, including NMDA receptors, in addition to inhibiting Na+ channels.

Is bupivacaine an Nsaid?

A local anesthetic is bupivacaine. By suppressing impulses at the nerve terminals, it reduces pain and creates a lack of sensation. No awareness is lost as a result of it. Nonsteroidal anti-inflammatory medication (NSAID) meloxicam