Caffeine Impurities

In times of exhaustion or sleepiness, caffeine is utilized to restore mental alertness or wakefulness.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Caffeine CRS (C0100000) Caffeine

Caffeine CRS (C0100000)

PVE0044 58-08-2
Caffeine EP Impurity A Caffeine/ Pentoxifylline/ Diprophylline/ Dimenhydrinate

Caffeine EP Impurity A

VL3710003 58-55-9
Caffeine EP Impurity C Caffeine

Caffeine EP Impurity C

VE0013128 519-32-4
Caffeine EP Impurity D Caffeine / Pentoxifylline

Caffeine EP Impurity D

VL3710004 83-67-0
Caffeine EP Impurity E Caffeine

Caffeine EP Impurity E

VE0015582 20041-90-1
Caffeine EP Impurity E (HCl Salt) Caffeine

Caffeine EP Impurity E (HCl Salt)

VE0013129 107605-95-8
Caffeine EP Impurity F Caffeine

Caffeine EP Impurity F

VE0013130 611-59-6
Caffeine for system suitability CRS Caffeine

Caffeine for system suitability CRS

PVE004 58-08-2
Caffeine Impurity 1 (Na Salt) Caffeine

Caffeine Impurity 1 (Na Salt)

VE0013158 N/A
Caffeine-D3 Caffeine


DVE00278 26351-04-2
Caffeine-D9 Caffeine


DVE00279 72238-85-8

Caffeine Related Compound

Additionally, several painkillers and migraine treatments, some nutritional supplements, and many well-known energy drinks also include caffeine.



Can caffeine be therapeutic?

In preterm newborns, intermittent breathing pauses (apnea) are treated with caffeine. Caffeine might lessen the acute discomfort associated with some diseases, such as migraines, when it is added to regularly prescribed pain medications (like paracetamol).

What is the therapeutic class of caffeine?

The most popular psychoactive stimulant used worldwide is caffeine, a naturally occurring methylxanthine class central nervous system (CNS) stimulant.

What is the mechanism of caffeine?

Caffeine causes relative brain hypoperfusion by increasing energy consumption throughout the brain while simultaneously decreasing cerebral blood flow. Caffeine appears to impact the local release of dopamine through activating noradrenaline neurons.