Efinaconazole Impurities

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Des-4-Methylenepiperidine Efinaconazole Efinaconazole

Des-4-Methylenepiperidine Efinaconazole

VE0010907 241479-72-1
Efinaconazole (2R,3S)-Diol Impurity Efinaconazole

Efinaconazole (2R,3S)-Diol Impurity

VE0015283 135270-11-0
Efinaconazole (2S)-Propiophenone Efinaconazole

Efinaconazole (2S)-Propiophenone

VE0014243 127001-03-0
Efinaconazole Hydroxy Impurity Efinaconazole

Efinaconazole Hydroxy Impurity

VE0012649 N/A
Efinaconazole Impurity 13 Efinaconazole

Efinaconazole Impurity 13

VE0014246 126918-16-9
Efinaconazole Impurity 15 Efinaconazole

Efinaconazole Impurity 15

VE0014248 2122222-14-2
Efinaconazole Impurity 16 Efinaconazole

Efinaconazole Impurity 16

VE0014249 126918-17-0
Efinaconazole Impurity 18 Efinaconazole

Efinaconazole Impurity 18

VE0014250 135133-23-2
Efinaconazole Impurity 2 Efinaconazole

Efinaconazole Impurity 2

VE0014244 159635-49-1
Efinaconazole Impurity 20 Efinaconazole

Efinaconazole Impurity 20

VE0014696 N/A
Efinaconazole Impurity 30 Efinaconazole

Efinaconazole Impurity 30

VE0015720 146432-17-9
Efinaconazole Impurity 31 (Mixture of Diastereomers) Efinaconazole

Efinaconazole Impurity 31 (Mixture of Diastereomers)

VE0014704 135206-86-9
Efinaconazole Impurity 35 (Mesylate Salt) Efinaconazole

Efinaconazole Impurity 35 (Mesylate Salt)

VE0014252 1175536-50-1
Efinaconazole Impurity 35 (Mesylate) Efinaconazole

Efinaconazole Impurity 35 (Mesylate)

VE0014693 1175536-50-1
Efinaconazole Impurity 38 Efinaconazole

Efinaconazole Impurity 38

VE0014689 164650-45-7
Efinaconazole Impurity 39 Efinaconazole

Efinaconazole Impurity 39

VE0014690 135270-07-4
Efinaconazole Impurity 41 Efinaconazole

Efinaconazole Impurity 41

VE0014251 135270-13-2
Efinaconazole Impurity 42 Efinaconazole

Efinaconazole Impurity 42

VE0012647 2252350-12-0
Efinaconazole Impurity 5 Efinaconazole

Efinaconazole Impurity 5

VE0012644 2055912-03-1
Efinaconazole Impurity 51 (Chloride) Efinaconazole

Efinaconazole Impurity 51 (Chloride)

VE0014699 N/A
Efinaconazole Impurity 51 (Methanesulfonate) Efinaconazole

Efinaconazole Impurity 51 (Methanesulfonate)

VE0014702 N/A
Efinaconazole Impurity 53 Efinaconazole

Efinaconazole Impurity 53

VE0014700 N/A
Efinaconazole Impurity 6 (HCl Salt) Efinaconazole

Efinaconazole Impurity 6 (HCl Salt)

VE0014245 41979-39-9
Efinaconazole N-Oxide Efinaconazole

Efinaconazole N-Oxide

VE0014255 2055038-63-4
Efinaconazole-D4 Efinaconazole

Efinaconazole-D4

DVE00567 N/A
N Methylpirrolidone Efinaconazole

N Methylpirrolidone

VL2260007 872-50-4
R S Diastereomer Efinaconazole Efinaconazole

R S Diastereomer Efinaconazole

VL2260004 2055038-60-1
S R Diastereomer Efinaconazole Efinaconazole

S R Diastereomer Efinaconazole

VL2260002 2055038-61-2
S,S Diastereomer Efinaconazole Efinaconazole

S,S Diastereomer Efinaconazole

VL2260005 N/A
(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate Efinaconazole

(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate

VE0014254 133775-26-5
2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran Efinaconazole

2-((R)-1-((R)-2-(2,4-Difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran

VE0010905 135267-12-8
4 Methylenpiperidine Hydrochloride Efinaconazole

4 Methylenpiperidine Hydrochloride

VL2260006 144230-50-2