Macitentan Impurities

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Hydroxy Macitentan Macitentan

Hydroxy Macitentan

VE0011423 2365406-85-3
Macitentan Impurity 13 Macitentan

Macitentan Impurity 13

VE0016573 2211054-46-3
Macitentan Impurity 14 Macitentan

Macitentan Impurity 14

VE0016574 2211059-05-9
Macitentan Impurity 15 Macitentan

Macitentan Impurity 15

VE0015365 N/A
Macitentan Impurity 16 Macitentan

Macitentan Impurity 16

VE0016576 2211059-00-4
Macitentan Impurity 17 Macitentan

Macitentan Impurity 17

VE0016577 N/A
Macitentan Impurity 25 Macitentan

Macitentan Impurity 25

VE0016578 1246922-88-2
Macitentan Impurity 7 Macitentan

Macitentan Impurity 7

VE0016571 1433875-14-9
Macitentan Impurity 8 Macitentan

Macitentan Impurity 8

VE0016572 556796-88-4
Macitentan Impurity A Macitentan

Macitentan Impurity A

VL3630001 441798-25-0
Macitentan Impurity A Macitentan

Macitentan Impurity A

VE0010276 1433875-21-8
Macitentan Impurity B Macitentan

Macitentan Impurity B

VE0010290 2211054-90-7
Macitentan Impurity C Macitentan

Macitentan Impurity C

VE0010291 441798-36-3
Macitentan Impurity D Macitentan

Macitentan Impurity D

VE0010292 2089065-77-8
Macitentan Impurity-15 Macitentan

Macitentan Impurity-15

VE0016575 2211054-17-8
Macitentan Pyrimidine N-Propyl Macitentan

Macitentan Pyrimidine N-Propyl

VE0011421 N/A
Macitentan-D4 Macitentan

Macitentan-D4

DVE00874 1258428-05-5
N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide Macitentan

N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide

VE0011371 1393813-43-8
N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide Macitentan

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide

VE0011372 1393813-42-7
N-[5-(4-Chlorophenyl)-6-[2-[(5-chloro-2-pyrimidinyl)oxy]ethoxy]4-pyrimidinyl]-N'-propylsulfamide Macitentan

N-[5-(4-Chlorophenyl)-6-[2-[(5-chloro-2-pyrimidinyl)oxy]ethoxy]4-pyrimidinyl]-N'-propylsulfamide

VE0011122 N/A
N-Despropyl Macitentan Macitentan

N-Despropyl Macitentan

VE0011424 1103522-45-7
N-Despropyl-N-Ethyl Macitentan Macitentan

N-Despropyl-N-Ethyl Macitentan

VE0011373 441796-13-0
N-Nitroso Macitentan Macitentan

N-Nitroso Macitentan

VE0014976 N/A
5-(4-Bromophenyl)-4,6-dichloropyrimidine Macitentan

5-(4-Bromophenyl)-4,6-dichloropyrimidine

VE0013249 146533-41-7
5-(4-Bromophenyl)pyrimidine-4,6-diol Macitentan

5-(4-Bromophenyl)pyrimidine-4,6-diol

VE0013247 706811-25-8
5-Bromo-2-chloropyrimidine Macitentan

5-Bromo-2-chloropyrimidine

VE0011370 32779-36-5