| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Memantine | Memantine 3, 5-Dimethyl-7-nitroadamantan-1-ol | VE006400 | View |
| Memantine | Memantine Hydrochloride | VL180007 | View CAS 41100-52-1 |
| Memantine | Memantine Lactose Adduct | VL180014 | View CAS 1159637-28-1 |
| Memantine | Memantine Related Compound A | VL180008 | View CAS 702-79-4 |
| Memantine | Memantine Related Compound B | VL180010 | View CAS 707-37-9 |
| Memantine | Memantine Related Compound C | VL180009 | View CAS 707-36-8 |
| Memantine | Memantine Related Compound D | VL180001 | View CAS 941-37-7 |
| Memantine | Memantine Related Compound F | VE006496 | View CAS 356572-08-2 |
| Memantine | Memantine Related Compound H | VE008323 | View CAS 15210-60-3 |
| Memantine | Memantine Related Compound I | VE008324 | View CAS 80121-67-1 |
| Memantine | Memantine RelatedCompound E | VL180002 | View CAS 351329-88-9 |
| Memantine | N-Acetyl Memantine | VL180013 | View CAS 19982-07-1 |
| Memantine | 1, 3, 5-Trimethyladamantane | VE008115 | View CAS 707-35-7 |
| Memantine | 1-Adamantamine hydrochloride | VL180006 | View CAS 665-66-7 |
| Memantine | 1-Amino-3-Hydroxy-5, 7-Dimethyl Adamantane | VE0010932 | View CAS 63971-25-5 |
| Memantine | 3-Methyl-Adamantamine | VL180011 | View CAS 33103-93-4 |
Memantine Related Compound
It is used to treat memory loss, which is one of dementia’s key symptoms. It is also used to treat Alzheimer’s disease symptoms.
References
- “Memantine: MedlinePlus Drug Information.” Medlineplus.gov, 2016, medlineplus.gov/druginfo/meds/a604006.html#:~:text=Memantine%20is%20in%20a%20class,in%20people%20who%20have%20AD. Accessed 30 May 2023.
- “Cholinesterase Inhibitors and Memantine for Dementia.” Nih.gov, National Institute for Health and Care Excellence (NICE), June 2018, www.ncbi.nlm.nih.gov/books/NBK536484/#:~:text=The%20three%20cholinesterase%20inhibitors%2C%20donepezil,(O’Brien%202017). Accessed 30 May 2023.
- Félix Javier Jiménez-Jiménez, et al. Anti-Inflammatory Effects of Amantadine and Memantine: Possible Therapeutics for the Treatment of Covid-19? no. 4, Nov. 2020, pp. 217–17, https://doi.org/10.3390/jpm10040217. Accessed 30 May 2023.
FAQ
What is the drug memantine classified as?
Memantine belongs to a family of drugs known as NMDA receptor antagonists. It works by reducing aberrant brain activity. Memantine may help or reduce the decline of cognitive and memory functions in persons with Alzheimer’s disease.
What type of inhibitor is memantine?
The only effective approved medicines for dementia are three cholinesterase inhibitors, donepezil, rivastigmine, galantamine, and the NMDA receptor antagonist, memantine.
Is memantine an anti-inflammatory?
Memantine has shown anti-inflammatory effects on human microvascular endothelium induced by the pro-inflammatory cytokine TNF-α in an experimental in vitro blood-brain-barrier (BBB) model of human brain microvascular endothelial cells.
