Moxifloxacin Impurities

Moxifloxacin, a powerful antibiotic, is instrumental in combating a diverse spectrum of bacterial infections.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Ciprofloxacin Difluoro 8-Methoxy Impurity Moxifloxacin

Ciprofloxacin Difluoro 8-Methoxy Impurity

VL239003 112811-72-0
Di-Nitroso-Pyrrolopiperidine (DNPP) Moxifloxacin

Di-Nitroso-Pyrrolopiperidine (DNPP)

VE0020329 N/A
Moxifloxacin 7-Amino Impurity Moxifloxacin

Moxifloxacin 7-Amino Impurity

VL106018 172426-88-9
Moxifloxacin 8-Hydroxy Quinolic Acid Moxifloxacin

Moxifloxacin 8-Hydroxy Quinolic Acid

VL239002 154093-72-8
Moxifloxacin Decarboxy Impurity Moxifloxacin

Moxifloxacin Decarboxy Impurity

VL106006 1322062-57-6
Moxifloxacin Difluoro Acid Impurity Moxifloxacin

Moxifloxacin Difluoro Acid Impurity

VL106017 93107-30-3
Moxifloxacin Difluoro Hydroxy Ethyl Ester Moxifloxacin

Moxifloxacin Difluoro Hydroxy Ethyl Ester

VE0018197 452092-31-8
Moxifloxacin Difluoro Methoxy Ethyl Ester Moxifloxacin

Moxifloxacin Difluoro Methoxy Ethyl Ester

VE008858 112811-71-9
Moxifloxacin Difluoro methyl ester Moxifloxacin

Moxifloxacin Difluoro methyl ester

VL106016 141290-02-0
Moxifloxacin Enantiomer-D4 (HCl Salt) Moxifloxacin

Moxifloxacin Enantiomer-D4 (HCl Salt)

DVE001131 N/A
Moxifloxacin EP Impurity A Moxifloxacin

Moxifloxacin EP Impurity A

VL106001 151213-15-9
Moxifloxacin EP Impurity B Moxifloxacin

Moxifloxacin EP Impurity B

VL106002 1029364-73-5
Moxifloxacin EP Impurity C (HCl salt) Moxifloxacin

Moxifloxacin EP Impurity C (HCl salt)

VL106003 1029364-75-7
Moxifloxacin EP Impurity D Moxifloxacin

Moxifloxacin EP Impurity D

VL106004 1029364-77-9
Moxifloxacin EP Impurity E Moxifloxacin

Moxifloxacin EP Impurity E

VL106005 721970-36-1
Moxifloxacin EP Impurity E (2HCl) Moxifloxacin

Moxifloxacin EP Impurity E (2HCl)

VE009652 N/A
Moxifloxacin EP Impurity F Moxifloxacin

Moxifloxacin EP Impurity F

VL106009 1350716-67-4
Moxifloxacin Ethyl Analog (Free Base) Moxifloxacin

Moxifloxacin Ethyl Analog (Free Base)

VE008397 1029364-75-7
Moxifloxacin Ethyl Ester Moxifloxacin

Moxifloxacin Ethyl Ester

VE008859 1403836-23-6
Moxifloxacin Hydroxy Acid Moxifloxacin

Moxifloxacin Hydroxy Acid

VL106008 N/A
Moxifloxacin Impurity 12 Moxifloxacin

Moxifloxacin Impurity 12

VE0019221 1395056-41-3
Moxifloxacin Impurity 15 Moxifloxacin

Moxifloxacin Impurity 15

VE0017984 N/A
Moxifloxacin Impurity 20 HCl Moxifloxacin

Moxifloxacin Impurity 20 HCl

VE000127 959347-97-8
Moxifloxacin Impurity 48 Moxifloxacin

Moxifloxacin Impurity 48

VE0018183 N/A
Moxifloxacin Impurity 58 Moxifloxacin

Moxifloxacin Impurity 58

VE0017620 1803729-19-2
Moxifloxacin Impurity 85 Moxifloxacin

Moxifloxacin Impurity 85

VE0017781 1620445-12-6
Moxifloxacin Methyl Ester Moxifloxacin

Moxifloxacin Methyl Ester

VL106007 721970-35-0
Moxifloxacin Related Compound A Nitroso Impurity Moxifloxacin

Moxifloxacin Related Compound A Nitroso Impurity

VE0011337 N/A
Moxifloxacin Related Compound B Nitroso Impurity Moxifloxacin

Moxifloxacin Related Compound B Nitroso Impurity

VE0011338 N/A
Moxifloxacin Related Compound C Nitroso Impurity Moxifloxacin

Moxifloxacin Related Compound C Nitroso Impurity

VE0011339 N/A
Moxifloxacin Related Compound D Nitroso Impurity Moxifloxacin

Moxifloxacin Related Compound D Nitroso Impurity

VE0011340 N/A
Moxifloxacin Related Compound F Moxifloxacin

Moxifloxacin Related Compound F

VL106019 1179992-99-4
Moxifloxacin Related Compound G Moxifloxacin

Moxifloxacin Related Compound G

VL106010 1346603-25-5
Moxifloxacin Related Compound G (Free Base) Moxifloxacin

Moxifloxacin Related Compound G (Free Base)

VE009489 268545-13-7
Moxifloxacin Related Compound G (HCl Salt) Moxifloxacin

Moxifloxacin Related Compound G (HCl Salt)

VE0011551 1394029-14-1
Moxifloxacin Related Compound G (Hydrochloride Monohydrate) Moxifloxacin

Moxifloxacin Related Compound G (Hydrochloride Monohydrate)

VE006991 N/A
Moxifloxacin Related Compound G Nitroso Impurity Moxifloxacin

Moxifloxacin Related Compound G Nitroso Impurity

VE0011341 N/A
Moxifloxacin-D4 (HCl Salt) Moxifloxacin

Moxifloxacin-D4 (HCl Salt)

DVE001130 N/A
Moxifloxanin N-Methyl Nonane Moxifloxacin

Moxifloxanin N-Methyl Nonane

VL106012 151213-45-5
N-Nitroso Moxifloxacin Moxifloxacin

N-Nitroso Moxifloxacin

VE008036 N/A
(1R,6R)-2,8-Diazabicyclo[4.3.0]nonane Moxifloxacin

(1R,6R)-2,8-Diazabicyclo[4.3.0]nonane

VE0015556 151213-42-2
(1S,6S)-2,8-Diazabicyclo[4.3.0]nonane Moxifloxacin

(1S,6S)-2,8-Diazabicyclo[4.3.0]nonane

VE0019700 151213-40-0
8-Methoxy quinolonic ethyl ester Moxifloxacin

8-Methoxy quinolonic ethyl ester

VL106015 N/A

Moxifloxacin Related Compound

Impurities in Moxifloxacin, typically residues from the synthesis process or degradation products, are essential to monitor and control, ensuring the drug’s quality remains uncompromised.

FAQ’s

What are the prevalent impurities in Moxifloxacin?

Moxifloxacin impurities can range from unreacted starting materials and intermediates to various degradation products.

What measures are in place to manage impurities in Moxifloxacin?

Rigorous testing and adherence to regulatory guidelines ensure impurities remain within acceptable boundaries.