Naratriptan Impurities and Related Compound

Naratriptan Impurities

Naratriptan is a selective serotonin (5-HT₁B/1D) receptor agonist used for the acute treatment of migraine attacks with or without aura. It belongs to the triptan class of medications and works by causing vasoconstriction of cranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides.
Naratriptan is typically administered orally and is known for its longer half-life compared to other triptans, offering sustained relief with a lower recurrence rate.
Indications include:
∙ Acute treatment of migraine headaches
∙ Relief from associated symptoms such as nausea, photophobia, and phonophobia

Structure

Product Name

CAS No.

Cat No.

Action

Bisaryl Naratriptan

Parent: Naratriptan

CAS No.: 1346604-16-7

Cat No.: VE009124

Naratriptan Impurities

Bisaryl Naratriptan

N-Benzyloxy Naratriptan-D3

N-Methyl-1-(4-nitrophenyl)methanesulfonamide

N-Methyl-1-(phenylmethyl)-3-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)-1H-indole-5-ethanesulfonamide

N-methyl-2-(1-(3-methylpiperidin-4-yl)-1H-indol-5-yl)-N-(2-(methylsulfonyl)ethyl)ethane-1-sulfonamide

N-methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)-2-(3-(1-nitrosopiperidin-4-yl)-1H-indol-5-yl)ethanesulfonamide

N-Methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)-N-(2-(N-methylsulfamoyl)ethyl)ethanesulfonamide

N-methyl-2-(3-(1-nitroso-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl)ethanesulfonamide

N-Methylethenesulfonamide

N-Nitroso Naratriptan

N-Nitroso Naratriptan (Chloride Salt)

N-Sulfamoylethyl Naratriptan

N-Sulfamoylethyl Naratriptan Pyridinium

N’-(2-Methylsulfamoylethyl) Naratriptan Hydrochloride

Naratriptan 2-Carboxylic Acid

Naratriptan 2-Carboxylic Acid (HCl Salt)

Naratriptan Impurity 4

Naratriptan Impurity 9

Naratriptan Inhouse Impurity B

Naratriptan N-Oxide

Naratriptan Pyridinium

Naratriptan Pyridinium Chloride

Naratriptan Pyridinium Salt

Naratriptan Related compound A (HCl Salt)

Naratriptan Related Compound B (Oxalate Salt)

Naratriptan-D3

Naratriptan-D3 (HCl Salt)

(1E)-N-Methyl-2-[1-(phenylmethyl)-1H-indol-5-yl]ethenesulfonamide

2-(1H-Indol-5-yl)-N-methylethanesulfonamide

2,2'-(3-(1-nitrosopiperidin-4-yl)-1H-indole-1,5-diyl)bis(N-methylethanesulfonamide)

3-(1-Methyl-4-piperidinyl)-1H-indole

4-(1,5-bis(2-(N-methylsulfamoyl)ethyl)-1H-indol-3-yl)-1-nitrosopyridin-1-ium

4-(5-(2-(N-methylsulfamoyl)ethyl)-1H-indol-3-yl)-1-nitrosopyridin-1-ium

4-Pyridinemethanol

5-Bromo-3-(1-methyl-4-piperidinyl)indole

5-Ethyl-3-(1-methylpiperidin-4-yl)-1H-indole

Naratriptan Related Compound

Types of Impurities in Naratriptan

FAQ

What is Naratriptan used for?

How does Naratriptan work?

What are the common side effects of Naratriptan?

Can Naratriptan be used during pregnancy?

How is Naratriptan different from Sumatriptan?