Nicorandil Impurities

Nicorandil is a medication used to treat and lessen angina-related chest discomfort.

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Nebivolol Related Compound

Your blood vessels are made more open and relaxed, which increases the flow of blood and oxygen to your heart.

References

  • Frampton, James E., et al. “Nicorandil.” Drugs, vol. 44, no. 4, Springer International Publishing, Oct. 1992, pp. 625–55, https://doi.org/10.2165/00003495-199244040-00008. Accessed 21 Apr. 2023.
  • Tarkin, Jason M., and Juan Carlos Kaski. “Vasodilator Therapy: Nitrates and Nicorandil.” Cardiovascular Drugs and Therapy, vol. 30, no. 4, Springer Science+Business Media, June 2016, pp. 367–78, https://doi.org/10.1007/s10557-016-6668-z. Accessed 21 Apr. 2023.
  • “ Nicorandil for Angina.” Drug and Therapeutics Bulletin, vol. 33, no. 12, BMJ, Dec. 1995, pp. 89–91, https://doi.org/10.1136/dtb.1995.331289. Accessed 21 Apr. 2023. ‌

FAQ

What is the therapeutic class of nicorandil?

Nicorandil is a member of the group of substances known as potassium channel activators, which are distinguished by their capacity to relax blood vessels.

Is nicorandil a vasodilator?

Nicorandil is a balanced vasodilator that opens arterial K+ ATP channels and donates NO. Nicorandil could possibly have cardioprotective effects through ischemia preconditioning of the mitochondria.

Is Nicorandil a calcium channel blocker?

Nicorandil increases the outflow of potassium ions via opening ATP-dependent potassium channels in vascular smooth muscle. This has a similar effect to calcium-channel blockers in that it hyperpolarizes the cell membrane, prevents calcium entry, and causes arteries and arterioles to widen.