Nitrofurazone is a topical antibacterial agent used to treat skin infections, especially in cases of burns, wounds, ulcers, and post-surgical incisions. It belongs to the class of nitrofuran antibiotics and exhibits broad-spectrum activity against Gram-positive and Gram-negative bacteria.
Nitrofurazone works by interfering with bacterial enzymes involved in carbohydrate metabolism and nucleic acid synthesis, leading to cell death. It is commonly formulated as ointment or cream and applied directly to the affected area.
It is also used veterinarily in animals for treating infections in skin, eyes, ears, and wounds.
Parent: Nifuroxazide / Nitrofurazone
Parent: Nitrofurazone/ Nifuroxazide
Nitrofurazone impurities may originate from synthetic processes, photodegradation, or formulation instability. Controlling these impurities is essential to ensure drug safety and regulatory compliance.
Process-Related Impurities
Degradation Impurities
Elemental Impurities
Analytical Techniques for Impurity Detection
Nitrofurazone is used to treat:
Common side effects:
