Nitroso Impurities

Nitroso impurities standards help to identify and quantitate nitrosamines in drug products during the manufacturing process.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Abacavir Nitroso 1 Abacavir

Abacavir Nitroso 1

VE007065 N/A
ABCRC-1 Dinitroso Impurity Abacavir

ABCRC-1 Dinitroso Impurity

VE007759 N/A
ABCRC-1 Nitroso Impurity-1 Abacavir

ABCRC-1 Nitroso Impurity-1

VE007757 N/A
ABCRC-1 Nitroso Impurity-2 Abacavir

ABCRC-1 Nitroso Impurity-2

VE007758 N/A
Acarbose Nitroso Impurity 1 Acarbose

Acarbose Nitroso Impurity 1

VE0011237 N/A
Avanafil Nitroso Impurity 1 Avanafil

Avanafil Nitroso Impurity 1

VE0014150 N/A
Bosutinib Nitroso Impurity Bosutinib

Bosutinib Nitroso Impurity

VE0014894 N/A
Bromhexine EP Impurity C Bromhexine

Bromhexine EP Impurity C

VL24003 57365-08-9
Bupropion Nitroso Impurity Bupropion

Bupropion Nitroso Impurity

VE009664 2763780-10-3
Carvedilol Di-Nitroso Carvedilol

Carvedilol Di-Nitroso

VE0010478 N/A
Cilnidipine Nitroso Impurity Cilnidipine

Cilnidipine Nitroso Impurity

VE008671 N/A
Clevidipine Nitroso Impurity Clevidipine

Clevidipine Nitroso Impurity

VE0014062 N/A
Clomipramine EP Impurity E (Nitroso Impurity) Clomipramine

Clomipramine EP Impurity E (Nitroso Impurity)

VE009769 7458-08-4
Clomipramine EP Impurity F Nitroso Impurity Clomipramine

Clomipramine EP Impurity F Nitroso Impurity

VE0010055 78213-40-8
Dabigatran Nitroso Impurity Dabigatran

Dabigatran Nitroso Impurity

VE0018605 N/A
Darolutamide Nitroso Impurity Darolutamide

Darolutamide Nitroso Impurity

VE0010234 N/A
Dasatinib Nitroso Impurity Dasatinib

Dasatinib Nitroso Impurity

VE0011523 N/A
Di-Nitroso-Clonidine Clonidine

Di-Nitroso-Clonidine

VE0011406 148950-50-9
Diethyl 2-((nitroso(phenyl)amino)methylene)malonate Ivacaftor

Diethyl 2-((nitroso(phenyl)amino)methylene)malonate

VE0015138 N/A
Diethylamine Dinitroso Impurity -

Diethylamine Dinitroso Impurity

VE009666 13256-12-7
Diethylamine Nitroso Impurity -

Diethylamine Nitroso Impurity

VE009665 23834-30-2
DiNitroso Lapatinib Lapatinib

DiNitroso Lapatinib

VE0015665 N/A
Dinitroso Palbociclib Palbociclib

Dinitroso Palbociclib

VE0015659 N/A
Dinitroso-Methyl piperazine Gatifloxacin Gatifloxacin

Dinitroso-Methyl piperazine Gatifloxacin

VE008163 55556-94-0
Elagolix Ethyl Ester Nitroso Impurity Elagolix

Elagolix Ethyl Ester Nitroso Impurity

VE009692 N/A
Elagolix Nitroso Impurity Elagolix

Elagolix Nitroso Impurity

VE009406 N/A
Eletriptan Nitroso Impurity Eletriptan

Eletriptan Nitroso Impurity

VE0010500 N/A
Erlotinib Nitroso Impurity Erlotinib

Erlotinib Nitroso Impurity

VE0015657 N/A
Ethyl 1-nitroso-1H-tetrazole-5-carboxylate Nitroso Impurity

Ethyl 1-nitroso-1H-tetrazole-5-carboxylate

VE0012581 N/A
Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate Ivacaftor

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate

VE0011351 N/A
Ezetimibe Nitroso Impurity Ezetimibe

Ezetimibe Nitroso Impurity

VE0010294 N/A
Ezetimibe Nitroso Impurity 1 Ezetimibe

Ezetimibe Nitroso Impurity 1

VE0010001 N/A
Ezetimibe Nitroso Impurity 2 Ezetimibe

Ezetimibe Nitroso Impurity 2

VE0010003 N/A
Fomepizole Nitroso Impurity Fomepizole

Fomepizole Nitroso Impurity

VE0014755 N/A
Frovatriptan Nitroso Impurity 1 Frovatriptan

Frovatriptan Nitroso Impurity 1

VE0010499 N/A
Frovatriptan Nitroso Impurity 2 Frovatriptan

Frovatriptan Nitroso Impurity 2

VE0010501 N/A
Granisetron Nitroso Impurity Granisetron

Granisetron Nitroso Impurity

VE0011607 N/A
Indacaterol Nitroso Impurity Indacaterol

Indacaterol Nitroso Impurity

VE0010331 N/A
Irbesartan Nitroso Impurity 1 Irbesartan

Irbesartan Nitroso Impurity 1

VE006176 N/A
Irbesartan Nitroso Impurity 2 Irbesartan

Irbesartan Nitroso Impurity 2

VE008461 N/A
Irbesartan Nitroso Spiro Impurity Irbesartan

Irbesartan Nitroso Spiro Impurity

VE006185 N/A
Isopropyl (2-amino-6-((4-fluorobenzyl)(nitroso)amino)pyridin-3-yl)carbamate Flupirtine

Isopropyl (2-amino-6-((4-fluorobenzyl)(nitroso)amino)pyridin-3-yl)carbamate

VE007901 N/A
Ivacaftor Nitroso Impurity Ivacaftor

Ivacaftor Nitroso Impurity

VE0010062 N/A
Lansoprazole Nitroso Impurity Lansoprazole

Lansoprazole Nitroso Impurity

VE007769 N/A
Levomefolate Nitroso Impurity 1 Levomefolic Acid

Levomefolate Nitroso Impurity 1

VE0014190 N/A
Levomefolate Nitroso Impurity 2 Levomefolic Acid

Levomefolate Nitroso Impurity 2

VE0014191 N/A
Linagliptin Nitroso Pyrimidine Impurity Linagliptin

Linagliptin Nitroso Pyrimidine Impurity

VE007060 6972-78-7
Lumateperone Nitroso Impurity 3 Lumateperone

Lumateperone Nitroso Impurity 3

VE009758 N/A
Methyl (2-amino-6-((4-fluorobenzyl)(nitroso)amino)pyridin-3-yl)carbamate Flupirtine

Methyl (2-amino-6-((4-fluorobenzyl)(nitroso)amino)pyridin-3-yl)carbamate

VE007903 N/A
methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib

methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

VE009404 N/A

Nitroso Related Compounds

We have successfully synthesis nitroso impurities like N-Nitroso-Ambroxol, N-Nitroso Pseudoephedrine, N-Nitroso Sertraline, N-Nitroso Ticagrelor, N-Nitroso Drotaverine, N-Nitroso Valsartan, N-Nitroso Pramipexole, N-Nitroso Salbutamol, N-Nitroso Escitalopram Impurity, N-Nitroso Olmesartan, N-Nitroso Fluoxetine, N-Nitroso Mirabegron, etc.

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