Paclitaxel Impurities

Show
per page

Paclitaxel Related Compound

PACLITAXEL is a chemotherapy medication. It targets rapidly dividing cells, such as cancer cells, and causes them to die. This drug is employed for treating tumors such as ovarian cancer, breast cancer, lung cancer, Kaposi’s sarcoma, and others.

References

  • “Facebook.” National Cancer Institute, Cancer.gov, 2017, www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/paclitaxel?redirect=true. Accessed 20 Mar. 2023.
  • Wang. “Paclitaxel-Induced Cell Death: Where the Cell Cycle and Apoptosis Come Together.” Cancer, vol. 88, no. 11, Cancer, 2023, https://doi.org/10.1002/1097-0142(20000601)88:11<2619::aid-cncr26>3.0.co;2-j. Accessed 20 Mar. 2023. ‌
  • Miers, Laird, et al. “Does Paclitaxel (Taxol) given after 111In-Labeled Monoclonal Antibodies Increase Tumor-Cumulated Activity in Epithelial Cancers?” Clinical Cancer Research, vol. 11, no. 19, Oct. 2005, pp. 7158s7163s, https://doi.org/10.1158/1078-0432.ccr-1004-0012. Accessed 20 Mar. 2023. ‌

FAQ

Is paclitaxel used as chemotherapy or as immunotherapy?

Chemotherapy medications, such as paclitaxel, function in many ways to inhibit tumor cell development, either by killing the cells, preventing them from growing, or preventing them from spreading.

Does paclitaxel induce apoptosis?

Paclitaxel inhibits cancer cells by inducing apoptosis, according to compelling data. Paclitaxel attaches to microtubules, causing them to be kinetically suppressed (stabilized).

Is paclitaxel a monoclonal antibody?

Paclitaxel enhanced the therapeutic impact of radiolabeled monoclonal antibodies in tests in mice with human xenografts. Paclitaxel was also found to boost tumor uptake in (111)In-DOTA-Gly3Phe-m170 imaging investigations in patients with breast and prostate cancer.