Paclitaxel Impurities

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Parent Drug Name Name of Impurity Catalogue No.
Paclitaxel N-Butyl Analog VL940002View
Paclitaxel Paclitaxel EP Impurity A VE008204View CAS 173101-54-7
Paclitaxel Paclitaxel EP Impurity B VE0010964View CAS 71610-00-9
Paclitaxel Paclitaxel EP Impurity C VE008208View CAS 153415-45-3
Paclitaxel Paclitaxel EP Impurity E VL940004View CAS 105454-04-4
Paclitaxel Paclitaxel EP Impurity G VE006502View CAS 78432-77-6
Paclitaxel Paclitaxel EP Impurity H VL940005View CAS 78454-17-8
Paclitaxel Paclitaxel EP Impurity I VE008205View CAS 2157462-42-3
Paclitaxel Paclitaxel EP Impurity J VE008206View
Paclitaxel Paclitaxel EP Impurity K VE009184View CAS 148930-55-6
Paclitaxel Paclitaxel EP Impurity L VE009186View CAS 92950-39-5
Paclitaxel Paclitaxel EP Impurity M VE008207View CAS 932042-85-8
Paclitaxel Paclitaxel EP Impurity N VE007275View CAS 27548-93-2
Paclitaxel Paclitaxel EP Impurity R VL940001View CAS 158948-96-0
Paclitaxel Paclitaxel Photodegradant Impurity VE0011526View

Paclitaxel Related Compound

PACLITAXEL is a chemotherapy medication. It targets rapidly dividing cells, such as cancer cells, and causes them to die. This drug is employed for treating tumors such as ovarian cancer, breast cancer, lung cancer, Kaposi’s sarcoma, and others.

References

  • “Facebook.” National Cancer Institute, Cancer.gov, 2017, www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/paclitaxel?redirect=true. Accessed 20 Mar. 2023.
  • Wang. “Paclitaxel-Induced Cell Death: Where the Cell Cycle and Apoptosis Come Together.” Cancer, vol. 88, no. 11, Cancer, 2023, https://doi.org/10.1002/1097-0142(20000601)88:11<2619::aid-cncr26>3.0.co;2-j. Accessed 20 Mar. 2023. ‌
  • Miers, Laird, et al. “Does Paclitaxel (Taxol) given after 111In-Labeled Monoclonal Antibodies Increase Tumor-Cumulated Activity in Epithelial Cancers?” Clinical Cancer Research, vol. 11, no. 19, Oct. 2005, pp. 7158s7163s, https://doi.org/10.1158/1078-0432.ccr-1004-0012. Accessed 20 Mar. 2023. ‌

FAQ

Is paclitaxel used as chemotherapy or as immunotherapy?

Chemotherapy medications, such as paclitaxel, function in many ways to inhibit tumor cell development, either by killing the cells, preventing them from growing, or preventing them from spreading.

Does paclitaxel induce apoptosis?

Paclitaxel inhibits cancer cells by inducing apoptosis, according to compelling data. Paclitaxel attaches to microtubules, causing them to be kinetically suppressed (stabilized).

Is paclitaxel a monoclonal antibody?

Paclitaxel enhanced the therapeutic impact of radiolabeled monoclonal antibodies in tests in mice with human xenografts. Paclitaxel was also found to boost tumor uptake in (111)In-DOTA-Gly3Phe-m170 imaging investigations in patients with breast and prostate cancer.

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105454-04-4: Paclitaxel EP Impurity E

105454-04-4: Paclitaxel EP Impurity E
Catalogue No.

VL940004

CAS No.

105454-04-4

Molecular Formula

C47H51NO14

Molecular Weight

853.91

Parent drug

Paclitaxel

IUPAC Name

7-Epipaclitaxel; 7-Epitaxol

Synonyms

7-Epi Paclitaxel

References

Sci-Hub, Peripheral Neuropathy Induced by Paclitaxel: Recent Insights and Future Perspectives, 10.2174/157015906776359568. Hkvisa.net. Published 2021. Accessed November 27, 2021. https://sci-hub.hkvisa.net/10.2174/157015906776359568 ?

Status

In-stock

ListName

Paclitaxel EP Impurity E

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