Rabeprazole Impurities

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Benzimidazole Rabeprazole

Benzimidazole

VL970014 51-17-2
N-[(4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl)methyl] Rabeprazole Sulfide Rabeprazole

N-[(4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl)methyl] Rabeprazole Sulfide

VE0017665 1114543-47-3
Rabeprazole 2-Chloromethyl Impurity Rabeprazole

Rabeprazole 2-Chloromethyl Impurity

VE0019785 153259-31-5
Rabeprazole Carboxylic Acid Impurity Rabeprazole

Rabeprazole Carboxylic Acid Impurity

VE0014311 1163685-31-1
Rabeprazole EP Impurity C Rabeprazole

Rabeprazole EP Impurity C

VL970011 2437254-50-5
Rabeprazole EP Impurity C Rabeprazole

Rabeprazole EP Impurity C

VE0014403 1163685-30-0
Rabeprazole EP Impurity D Rabeprazole

Rabeprazole EP Impurity D

VL970001 924663-40-1
Rabeprazole EP Impurity E Rabeprazole

Rabeprazole EP Impurity E

VL970013 102804-77-3
Rabeprazole EP Impurity G Rabeprazole

Rabeprazole EP Impurity G

VL970010 102804-82-0
Rabeprazole EP Impurity I Rabeprazole

Rabeprazole EP Impurity I

VL970003 924663-37-6
Budesonide for System Suitability CRS (Y0001148) Rabeprazole

Rabeprazole for System Suitability CRS (Y0001778)

PVE00306 891191-56-3
Rabeprazole Impurity 1 Rabeprazole

Rabeprazole Impurity 1

VE0019704 1286104-27-5
Rabeprazole Impurity 4 Rabeprazole

Rabeprazole Impurity 4

VE0018363 103312-62-5
Rabeprazole Impurity 8 Rabeprazole

Rabeprazole Impurity 8

VE0019976 1613482-73-7
Rabeprazole N-Alkyl Impurity Rabeprazole

Rabeprazole N-Alkyl Impurity

VE0019975 935260-92-7
Rabeprazole Picolinium Salt Impurity Rabeprazole

Rabeprazole Picolinium Salt Impurity

VE006108 1807988-36-8
Rabeprazole Related Compound 1 Rabeprazole

Rabeprazole Related Compound 1

VE0018287 117977-19-2
Rabeprazole Related Compound D Rabeprazole

Rabeprazole Related Compound D

VL970007 117976-47-3
Rabeprazole Related Compound E Rabeprazole

Rabeprazole Related Compound E

VL970008 117977-21-6
Rabeprazole Related Compound F Rabeprazole

Rabeprazole Related Compound F

VL970005 168167-42-8
Rabeprazole Sodium R-Isomer Rabeprazole

Rabeprazole Sodium R-Isomer

VE0010116 171440-18-9
Rabeprazole Sodium STAGE - I Rabeprazole

Rabeprazole Sodium STAGE - I

VL970002 117976-90-6
Rabeprazole Sulfide N-Oxide Rabeprazole

Rabeprazole Sulfide N-Oxide

VE0011778 924663-40-1
Rabeprazole-D4 (Na Salt) Rabeprazole

Rabeprazole-D4 (Na Salt)

DVE001422 N/A
Racemic-Desmethyl Rabeprazole (Sodium Salt) Rabeprazole

Racemic-Desmethyl Rabeprazole (Sodium Salt)

VE0011439 117976-71-3
Racemic-O-Desmethyl Rabeprazole Impurity Rabeprazole

Racemic-O-Desmethyl Rabeprazole Impurity

VE0011438 117976-94-0
(R)-O-Desmethyl Rabeprazole Impurity Rabeprazole

(R)-O-Desmethyl Rabeprazole Impurity

VE0011442 179952-04-6
(S)-Desmethyl Rabeprazole Sodium Salt Rabeprazole

(S)-Desmethyl Rabeprazole Sodium Salt

VE0011440 N/A
(S)-O-Desmethyl Rabeprazole Impurity Rabeprazole

(S)-O-Desmethyl Rabeprazole Impurity

VE0011441 179952-05-7
2-(Chloromethyl)-4-(3-methoxypropoxy)-3-methylpyridine 1-oxide Rabeprazole

2-(Chloromethyl)-4-(3-methoxypropoxy)-3-methylpyridine 1-oxide

VE009625 924663-39-8

Rabeprazole Related Compound

Rabeprazole is a drug that reduces stomach acid. It is used to treat peptic ulcers, gastroesophageal reflux disease, and excessive stomach acid production, such as in Zollinger-Ellison syndrome.

References

FAQ

What is the drug rabeprazole used for?

Rabeprazole is used to treat duodenal ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome, a disorder in which the stomach generates excessive amounts of acid. It may also be used in conjunction with antibiotics (e.g., amoxicillin, clarithromycin) to treat ulcers produced by H. influenzae infections.

Is rabeprazole a type of antacid?

Rabeprazole is part of a class of drugs known as proton-pump inhibitors. It reduces the quantity of acid produced in the stomach.

What is the mechanism of action of rabeprazole?

Rabeprazole is a proton pump inhibitor antiulcer medication. It is a prodrug that converts to active sulphenamide in the acid environment of the parietal cells. Rabeprazole inhibits the H+, K+ATPase of coated gastric cells and suppresses basal and induced stomach acid output in a dose-dependent manner.