Ranolazine Impurities and Related Compound

Structure

Product Name

CAS No.

Cat No.

Action

Lidocaine Dimer N-Oxide

Parent: Lidocaine / Ranolazine

CAS No.: 2725395-82-2

Cat No.: VE0016054

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m-Ranolazine

Parent: Ranolazine

CAS No.: 1393717-46-8

Cat No.: VL770017

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N-(2,4-dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0021719

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N-(2,6-Dimethylphenyl)-2-hydroxyacetamide

Parent: Ranolazine

CAS No.: 29183-14-0

Cat No.: VE0010656

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N-Nitroso Ranolazine

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0010066

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N-Nitroso Ranolazine Impurity 1

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0010326

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N-Nitroso Ranolazine Impurity 2

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0024720

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N-Nitroso Ranolazine Impurity 3

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0024731

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Nitroso Piperazine Acetamide

Parent: RANOLAZINE

CAS No.: 3038740-93-8

Cat No.: VE007754

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p-Ranolazine

Parent: Ranolazine

CAS No.: 1393717-45-7

Cat No.: VL770016

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Ranolazine Alcohol Dimer

Parent: Ranolazine

CAS No.: 333749-57-8

Cat No.: VL770010

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Ranolazine Dianisylglycerol

Parent: Ranolazine

CAS No.: 16929-60-5

Cat No.: VL770019

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Ranolazine ether dimer

Parent: Ranolazine

CAS No.: N/A

Cat No.: VL770018

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Ranolazine Impurity 3

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0019790

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Ranolazine Impurity C

Parent: Ranolazine

CAS No.: 2724549-66-8

Cat No.: VE0021561

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Ranolazine N-Desacetamido Impurity

Parent: Ranolazine

CAS No.: 162712-35-8

Cat No.: VL770015

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Ranolazine N,N-Dioxide Impurity

Parent: Ranolazine

CAS No.: 1246816-00-1

Cat No.: VL770002

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Ranolazine O-alkylated Impurity

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0021717

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Ranolazine O-desaryl impurity

Parent: Ranolazine

CAS No.: 172430-46-5

Cat No.: VL770014

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Ranolazine O-Desmethyl Impurity

Parent: Ranolazine

CAS No.: 172430-45-4

Cat No.: VL770021

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Ranolazine Related Compound A

Parent: Ranolazine

CAS No.: 2210-74-4

Cat No.: VL770008

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Ranolazine Related Compound B

Parent: Ranolazine

CAS No.: 755711-09-2

Cat No.: VL770009

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Ranolazine Related Compound C

Parent: Ranolazine

CAS No.: 5294-61-1

Cat No.: VL770004

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Ranolazine Related Compound D

Parent: Ranolazine

CAS No.: 380204-72-8

Cat No.: VL770003

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Ranolazine Working Standard (Secondary Reference Standard)

Parent: Ranolazine

CAS No.: 95635-55-5

Cat No.: VE0025931

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Ranolazine-D5

Parent: Ranolazine

CAS No.: N/A

Cat No.: DVE001461

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(S)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)-N-(p-tolyl)acetamide

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0021877

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2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)-N-(o-tolyl)acetamide

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0021721

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2-(4-(3-(2-chlorophenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide

Parent: Ranolazine

CAS No.: N/A

Cat No.: VE0021715

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Types of Impurities in Ranolazine

Process-Related Impurities

Unreacted intermediates from synthesis

Residual solvents (e.g., ethanol, methanol, acetone)

By-products from manufacturing

Degradation Impurities

Oxidative degradation (due to oxygen exposure)

Hydrolytic degradation (moisture-induced breakdown)

Photodegradation (chemical changes from light exposure)

Elemental Impurities

Heavy metals (e.g., lead, arsenic, mercury, cadmium)

Residual catalysts from synthesis

Analytical Techniques for Impurity Detection

High-Performance Liquid Chromatography (HPLC)

Gas Chromatography (GC)

Fourier-Transform Infrared Spectroscopy (FT-IR)

Mass Spectrometry (MS)

FAQ

Ranolazine Impurities

Lidocaine Dimer N-Oxide

m-Ranolazine

N-(2,4-dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide

N-(2,6-Dimethylphenyl)-2-hydroxyacetamide

N-Nitroso Ranolazine

N-Nitroso Ranolazine Impurity 1

N-Nitroso Ranolazine Impurity 2

N-Nitroso Ranolazine Impurity 3

Nitroso Piperazine Acetamide

p-Ranolazine

Ranolazine Alcohol Dimer

Ranolazine Dianisylglycerol

Ranolazine ether dimer

Ranolazine Impurity 3

Ranolazine Impurity C

Ranolazine N-Desacetamido Impurity

Ranolazine N,N-Dioxide Impurity

Ranolazine O-alkylated Impurity

Ranolazine O-desaryl impurity

Ranolazine O-Desmethyl Impurity

Ranolazine Related Compound A

Ranolazine Related Compound B

Ranolazine Related Compound C

Ranolazine Related Compound D

Ranolazine Working Standard (Secondary Reference Standard)

Ranolazine-D5

(S)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)-N-(p-tolyl)acetamide

2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)-N-(o-tolyl)acetamide

2-(4-(3-(2-chlorophenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide

Ranolazine Related Compound

Types of Impurities in Ranolazine

FAQ

What does ranolazine do for the heart?

What is the mechanism of action of ranolazine?

Is ranolazine a calcium channel blocker?

What drug group is ranolazine?