Parent Drug Name | Name of Impurity | Catalogue No. | |
---|---|---|---|
Rifampicin | Desacetyl Rifampicin Quinone | VE0011704 | View CAS 65110-92-1 |
Rifampicin | N-Demethyl Rifampicin | VE0011705 | View CAS 13292-45-0 |
Rifampicin | N-Methyl Rifampicin | VE0010080 | View |
Rifampicin | Rifampicin | VE007986 | View CAS 13292-46-1 |
Rifampicin | Rifampicin 21-O-Acetyl Analog | VE0011112 | View CAS 1416773-22-2 |
Rifampicin | Rifampicin 23-O-Acetyl Analog | VE0011113 | View CAS 1416773-23-3 |
Rifampicin | Rifampicin EP Impurity A | VL2760006 | View CAS 13983-13-6 |
Rifampicin | Rifampicin EP Impurity B | VL2760001 | View CAS 51963-55-4 |
Rifampicin | Rifamycin Impurity- 3(INHM) | VL2760007 | View |
Rifampicin | 25-Desacetyl rifampicin | VL2760004 | View CAS 16783-99-6 |
Rifampicin | 25-Desacetyl-21-acetyl rifampicin | VL2760005 | View CAS 1416773-22-2 |
Rifampicin | 3-Formylrifamycin SV | VL2760003 | View CAS 13292-22-3 |
Rifampicin | 4-Methylpiperazine-1-yl-imino Rifamycin O | VE0010081 | View |
Rifampicin Related Compound
Rifaximin belongs to the antibiotic drug class. Rifaximin cures traveler’s diarrhea and irritable bowel syndrome by inhibiting the development of the bacteria responsible for diarrhea.
References
- Saadi, Mohammed, and Richard W. McCallum. “Rifaximin in Irritable Bowel Syndrome: Rationale, Evidence and Clinical Use.” Therapeutic Advances in Chronic Disease, vol. 4, no. 2, Jan. 2013, pp. 71–75, https://doi.org/10.1177/2040622312472008. Accessed 14 Mar. 2023.
- DuPont, H. L. “Rifaximin: An Antibiotic with Important Biologic Effects.” Mini-Reviews in Medicinal Chemistry, vol. 16, no. 3, Nov. 2015, pp. 200–5, https://doi.org/10.2174/1389557515666150722110201. Accessed 14 Mar. 2023.
- “Rifaximin: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2015, go.drugbank.com/drugs/DB01220. Accessed 14 Mar. 2023.
FAQ
Why is rifaximin used in IBS?
The findings indicate that people with IBS have an overabundance of bacteria in the small bowel, a condition known as bacterial overgrowth. As a result, antibiotic-based therapies for IBS may be beneficial. Rifaximin is a nonabsorbable antibiotic with no clinically significant bacterial resistance.
Is rifaximin an anti-inflammatory?
The medicine possesses anti-inflammatory qualities that help to stabilize the gut mucosa, which is vital for its long-term benefits in non-infectious disorders. Rifaximin is used to treat hepatic encephalopathy and diarrhea-predominant irritable bowel syndrome on a long-term or recurring basis.
What is the mechanism of action of rifaximin?
Rifaximin inhibits RNA synthesis in sensitive bacteria by attaching to the beta subunit of the bacterial DNA-dependent ribonucleic acid (RNA) polymerase enzyme. Its binding prevents translocation and hence transcription.