Rosuvastatin Impurities

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Parent Drug Name Name of Impurity Catalogue No.
Rosuvastatin Rosuvastatin (3R, 5R)-Isomer (Free Base) VE0010480View CAS 1094100-06-7
Rosuvastatin Rosuvastatin (3R, 5R)-Isomer Calcium VE008031View CAS 1422515-55-6
Rosuvastatin Rosuvastatin (3R, 5R)-Isomer t-Butyl Ester VL127023View CAS 2162136-65-2
Rosuvastatin Rosuvastatin (3R, 5S)-Isomer Methyl Ester VE006590View
Rosuvastatin Rosuvastatin (6R)-Isomer Calcium Salt VE009138View CAS 854898-49-0
Rosuvastatin Rosuvastatin (6R)-Isomer Sodium Salt VE008979View CAS 854898-48-9
Rosuvastatin Rosuvastatin (6R)-Lactone Impurity VE008982View CAS 854898-46-7
Rosuvastatin Rosuvastatin (6S)-Lactone Impurity VE008981View CAS 854898-47-8
Rosuvastatin Rosuvastatin 2, 3-Anhydro Acid VL127021View CAS 1422954-12-8
Rosuvastatin Rosuvastatin 3S 5S isomer VL127007View
Rosuvastatin Rosuvastatin 4, 6-Diene Impurity VL127024View CAS 1422954-13-9
Rosuvastatin Rosuvastatin 5-Hydroxy-3-keto VL127033View CAS 1346606-28-7
Rosuvastatin Rosuvastatin 5-Oxo Acid t-Butyl Ester VE008985View CAS 615556-96-2
Rosuvastatin Rosuvastatin Acetonide Carboxylic Acid VE006456View
Rosuvastatin Rosuvastatin Acid Impurity VL127020View CAS 1659301-59-3
Rosuvastatin Rosuvastatin Ally Ester Impurity VL127031View CAS 1352945-05-1
Rosuvastatin Rosuvastatin Anhydro Lactone VL127032View CAS 1246665-85-9
Rosuvastatin Rosuvastatin Bromomethyl Impurity VL127027View CAS 799842-07-2
Rosuvastatin Rosuvastatin EP Impurity A VL127008View CAS 1714147-47-3
Rosuvastatin Rosuvastatin EP Impurity A (Sodium Salt) VE008146View CAS 1714147-50-8
Rosuvastatin Rosuvastatin EP Impurity B (Racemic Mixture) VL127001View
Rosuvastatin Rosuvastatin EP Impurity C VL127003View CAS 1422514-05-3
Rosuvastatin Rosuvastatin EP Impurity C (Free Base) VE0011116View CAS 1422619-13-3
Rosuvastatin Rosuvastatin EP Impurity D VL127002View CAS 503610-43-3
Rosuvastatin Rosuvastatin EP Impurity E VL127005View
Rosuvastatin Rosuvastatin EP Impurity F VL127004View CAS 289042-12-2
Rosuvastatin Rosuvastatin EP Impurity G VL127009View
Rosuvastatin Rosuvastatin EP Impurity G (Free Base) VE008147View CAS 1242184-42-4
Rosuvastatin Rosuvastatin EP Impurity H VL127015View CAS 1335110-44-5
Rosuvastatin Rosuvastatin EP Impurity I (sodium salt) VL127016View
Rosuvastatin Rosuvastatin EP Impurity J VL127014View
Rosuvastatin Rosuvastatin EP Impurity K VL127017View
Rosuvastatin Rosuvastatin EP Impurity L VL127006View CAS 1024064-70-7
Rosuvastatin Rosuvastatin EP Impurity M VL127018View
Rosuvastatin Rosuvastatin EP Impurity M (Free Base) VE006725View
Rosuvastatin Rosuvastatin Ethyl Ester Impurity VL127022View CAS 851443-04-4
Rosuvastatin Rosuvastatin FP Impurity B VE006136View CAS 287714-41-4
Rosuvastatin Rosuvastatin Formyl Impurity VL127025View CAS 147118-37-4
Rosuvastatin Rosuvastatin Hydroxy methyl Impurity VL127026View CAS 147118-36-3
Rosuvastatin Rosuvastatin Hydroxy propenyl Impurity VL127028View CAS 910867-08-2
Rosuvastatin Rosuvastatin Isoamy Ester VE008987View CAS 1197348-98-3
Rosuvastatin Rosuvastatin KSM (4S, 6R)-isomer VE008463View
Rosuvastatin Rosuvastatin Methyl Ester Impurity VL127012View CAS 147118-40-9
Rosuvastatin Rosuvastatin Tert Butyl Ester VL127010View CAS 355806-00-7
Rosuvastatin Rosuvastatin Z-Isomer VL127011View
Rosuvastatin Rosuvastatin Z-Isomer (Calcium Salt) VE006593View
Rosuvastatin Tert-Butyl (3S, 5S)-6-Chloro-3, 5-dihydroxyhexanoate VE008980View CAS 325471-28-1
Rosuvastatin tert-Butyl 6-Chloro-5(S)-hydroxy-3-oxohexanoate VE008577View CAS 154026-92-3
Rosuvastatin 3-Dehydro Rosuvastatin VL127013View
Rosuvastatin (3R, 5S)-6-Chloro-3, 5-dihydroxyhexanoic Acid tert-Butyl Ester VE008578View CAS 154026-93-4
Rosuvastatin (3S, 5R)-tert-Butyl 6-chloro-3, 5-dihydroxyhexanoate VE008984View CAS 404958-68-5
Rosuvastatin (4R-cis)-6-Chloromethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic Acid tert-Butyl Ester VE008579View CAS 154026-94-5
Rosuvastatin (R)-tert-Butyl 6-chloro-5-hydroxy-3-oxohexanoate VE008986View CAS 404958-08-3
Rosuvastatin (S)-4-chloro-3-hydroxybutanenitrile VE005859View CAS 127913-44-4

Rosuvastatin Related Compound

It works by inhibiting an enzyme required by the body to produce cholesterol, hence lowering the quantity of cholesterol in the blood.

References

  • “Rosuvastatin: MedlinePlus Drug Information.” Medlineplus.gov, 2021, www.medlineplus.gov/druginfo/meds/a603033.html. Accessed 20 Feb. 2023.
  • Lee, Sungjae, et al. “Antihypertensive Effects of Rosuvastatin in Patients with Hypertension and Dyslipidemia: A Systemic Review and Meta-Analysis of Randomized Studies.” PLOS ONE, edited by Mansueto Gomes Neto, vol. 16, no. 11, Nov. 2021, p. e0260391, https://doi.org/10.1371/journal.pone.0260391. Accessed 20 Feb. 2023.

FAQ’s

Rosuvastatin belongs to which family ?

Rosuvastatin belongs to a family of drugs known as HMG-CoA reductase inhibitors (statins).

Is rosuvastatin A an antihypertensive medication?

Rosuvastatin may help manage hypertension and, as a result, reduce the risk of cardiovascular events in people with hypertension and dyslipidemia.

What is the mechanism action of Rosuvastatin?

Rosuvastatin belongs to a family of drugs known as HMG-CoA reductase inhibitors (statins). It works by delaying the creation of cholesterol in the body, reducing the amount of cholesterol that can build up on the artery walls and obstruct blood flow to the heart, brain, and other organs.

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1024064-70-7: Rosuvastatin EP Impurity L

1024064-70-7: Rosuvastatin EP Impurity L
Catalogue No.

VL127006

CAS No.

1024064-70-7

Molecular Formula

C22H29FN3O6S. 1⁄2 Ca

Molecular Weight

482.55•20.08

Parent drug

Rosuvastatin

IUPAC Name

(3R, 5S)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-heptanoic acid calcium salt

Synonyms

Rosuvastatin 6, 7-Dihydro Impurity / Dihydro Rosuvastatin Calcium

References

'Sci-Hub, Synthesis and Characterization of Rosuvastatin Calcium Impurity A; a HMG-CoA Reductase Inhibitor. Tetrahedron Letters, 58(26), 2614–2617, 10.1016/J.tetlet.2017.05.075.” Sci-Hub.hkvisa.net, sci-hub.hkvisa.net/www.sciencedirect.com/science/article/abs/pii/S0040403917306688. Accessed 22 Feb. 2022.'

Status

In-stock

ListName

Rosuvastatin EP Impurity L

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