Sofosbuvir Impurities and Related Compound

Sofosbuvir Impurities

Sofosbuvir is an antiviral medication used in the treatment of chronic hepatitis C (HCV) infections. It is a nucleotide analog inhibitor of hepatitis C virus (HCV) NS5B RNA polymerase, which is essential for viral replication. Sofosbuvir is typically used in combination with other antiviral medications, such as ledipasvir, velpatasvir, or daclatasvir, to achieve sustained virologic response (SVR).

Structure

Product Name

CAS No.

Cat No.

Action

Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydrofuran-2-Yl)Methoxy)(Phenoxy)Phosphoryl)-D-Alaninate

Parent: Sofosbuvir

CAS No.: 1496552-28-3

Cat No.: VE009011

Sofosbuvir Impurities

Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydrofuran-2-Yl)Methoxy)(Phenoxy)Phosphoryl)-D-Alaninate

Methoxy Sofosbuvir Impurity

O-Desphenyl O-methyl Sofosbuvir

O-Desphenyl Sofosbuvir

Pentafluorophenol

Sofosbuvir 3',5'-Bis-(S)-phosphate

Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]

Sofosbuvir Impurity 102

Sofosbuvir Impurity 115

Sofosbuvir Impurity 117

Sofosbuvir Impurity 123

Sofosbuvir Impurity 13

Sofosbuvir Impurity 2

Sofosbuvir Impurity 23

Sofosbuvir Impurity 36

Sofosbuvir Impurity 45

Sofosbuvir Impurity 63

Sofosbuvir Impurity 64

Sofosbuvir Impurity 65

Sofosbuvir Impurity 9

Sofosbuvir Impurity 91

Sofosbuvir Impurity 99

Sofosbuvir IP Impurity A

Sofosbuvir IP Impurity B

Sofosbuvir IP Impurity D

Sofosbuvir Isomer Impurity 17

Sofosbuvir Methylene Impurity

Sofosbuvir Reference Standard

Sofosbuvir α-Isomer

((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl Phenyl Hydrogen Phosphate

(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate

(2R,3R,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

(S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

2'-Alkene Sofosbuvir

2'-Hydroxy Sofosbuvir

2’S-α-Fluoro tribenzoyl sofosbuvir intermidiate

2′-Alkene Mono-N-Benzoyl Sofosbuvir

2′-S-Fluoro sofosbuvir

3'-S Sofosbuvir isomer

Sofosbuvir Related Compound

Types of Impurities in Sofosbuvir

FAQ

When is the best time to take Sofosbuvir?

What are the precautions for Sofosbuvir?

What should you avoid while taking Epclusa (Sofosbuvir + Velpatasvir)?

How long is Sofosbuvir treatment?