Sofosbuvir Impurities

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydrofuran-2-Yl)Methoxy)(Phenoxy)Phosphoryl)-D-Alaninate Sofosbuvir

Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydrofuran-2-Yl)Methoxy)(Phenoxy)Phosphoryl)-D-Alaninate

VE009011 1496552-28-3
Methoxy Sofosbuvir Impurity Sofosbuvir

Methoxy Sofosbuvir Impurity

VE009018 1394157-34-6
O-Desphenyl O-methyl Sofosbuvir Sofosbuvir

O-Desphenyl O-methyl Sofosbuvir

VE009097 N/A
O-Desphenyl Sofosbuvir Sofosbuvir

O-Desphenyl Sofosbuvir

VE0019210 1233335-82-4
Pentafluorophenol Sofosbuvir

Pentafluorophenol

VE0018202 771-61-9
Sofosbuvir 3',5'-Bis-(S)-phosphate Sofosbuvir

Sofosbuvir 3',5'-Bis-(S)-phosphate

VE009034 1337482-17-3
Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate] Sofosbuvir

Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]

VE009016 1337482-15-1
Sofosbuvir Impurity 102 Sofosbuvir

Sofosbuvir Impurity 102

VE0019198 N/A
Sofosbuvir Impurity 123 Sofosbuvir

Sofosbuvir Impurity 123

VE0019216 119804-96-5
Sofosbuvir Impurity 13 Sofosbuvir

Sofosbuvir Impurity 13

VE0019205 119410-95-6
Sofosbuvir Impurity 2 Sofosbuvir

Sofosbuvir Impurity 2

VE0019201 863329-62-8
Sofosbuvir Impurity 36 Sofosbuvir

Sofosbuvir Impurity 36

VE0019208 N/A
Sofosbuvir Impurity 63 Sofosbuvir

Sofosbuvir Impurity 63

VE0019882 1334513-02-8
Sofosbuvir Impurity 9 Sofosbuvir

Sofosbuvir Impurity 9

VE0017831 863329-65-1
Sofosbuvir Impurity 91 Sofosbuvir

Sofosbuvir Impurity 91

VE0019213 817204-35-6
Sofosbuvir Impurity 99 Sofosbuvir

Sofosbuvir Impurity 99

VE0020309 2095880-39-8
Sofosbuvir IP Impurity A Sofosbuvir

Sofosbuvir IP Impurity A

VE009015 1190308-01-0
Sofosbuvir IP Impurity B Sofosbuvir

Sofosbuvir IP Impurity B

VE009023 1496552-51-2
Sofosbuvir IP Impurity D Sofosbuvir

Sofosbuvir IP Impurity D

VE009028 863329-66-2
Sofosbuvir Methylene Impurity Sofosbuvir

Sofosbuvir Methylene Impurity

VE009012 863329-63-9
Sofosbuvir α-Isomer Sofosbuvir

Sofosbuvir α-Isomer

VE009031 N/A
((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl Phenyl Hydrogen Phosphate Sofosbuvir

((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl Phenyl Hydrogen Phosphate

VE009013 1859162-80-3
(2R,3R,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate Sofosbuvir

(2R,3R,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

VE009032 N/A
(S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Sofosbuvir

(S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

VE009021 2164516-85-0
2'-Alkene Sofosbuvir Sofosbuvir

2'-Alkene Sofosbuvir

VE009109 2095551-20-3
2'-Hydroxy Sofosbuvir Sofosbuvir

2'-Hydroxy Sofosbuvir

VE009022 N/A
2’S-α-Fluoro tribenzoyl sofosbuvir intermidiate Sofosbuvir

2’S-α-Fluoro tribenzoyl sofosbuvir intermidiate

VE009111 N/A
2′-Alkene Mono-N-Benzoyl Sofosbuvir Sofosbuvir

2′-Alkene Mono-N-Benzoyl Sofosbuvir

VE009110 N/A
2′-S-Fluoro sofosbuvir Sofosbuvir

2′-S-Fluoro sofosbuvir

VE009098 N/A
3'-S Sofosbuvir isomer Sofosbuvir

3'-S Sofosbuvir isomer

VE009014 N/A