| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Sulfamethoxazole | Sulfamethoxazole EP Impurity A | VL1990005 | View CAS 21312-10-7 |
| Sulfamethoxazole | Sulfamethoxazole EP Impurity B | VL1990006 | View CAS 135529-16-7 |
| Sulfamethoxazole | Sulfamethoxazole EP Impurity C | VL1990003 | View CAS 1072-67-9 |
| Sulfamethoxazole | Sulfamethoxazole EP Impurity D | VL1990001 | View CAS 121-57-3 |
| Sulfamethoxazole | Sulfamethoxazole EP Impurity E | VL1990002 | View CAS 63-74-1 |
| Sulfamethoxazole | Sulfamethoxazole EP Impurity F | VL1990004 | View CAS 17103-52-5 |
Sulfamethoxazole Related Compound
Sulfamethoxazole is an oral sulfonamide antibiotic used to treat infections of the urinary tract, respiratory system, and gastrointestinal tract when combined with trimethoprim.
References
- “Sulfamethoxazole: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2015, go.drugbank.com/drugs/DB01015. Accessed 1 Feb. 2023.
- Masters, Philip A., et al. “Trimethoprim-Sulfamethoxazole Revisited.” Archives of Internal Medicine, vol. 163, no. 4, Feb. 2003, p. 402, https://doi.org/10.1001/archinte.163.4.402. Accessed 1 Feb. 2023.
- Lundstrom TS;Sobel JD. “Vancomycin, Trimethoprim-Sulfamethoxazole, and Rifampin.” Infectious Disease Clinics of North America, vol. 9, no. 3, Infect Dis Clin North Am, 2023, pubmed.ncbi.nlm.nih.gov/7490442/. Accessed 1 Feb. 2023.
FAQ’s
Sulfamethoxazole belongs to what drug class?
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that inhibits the production of folic acid in sensitive bacteria.
What is the mechanism of sulfamethoxazole?
Trimethoprim and sulfamethoxazole block bacterial production of tetrahydrofolic acid, a physiologically active form of folic acid that is required for the synthesis of thymidine, purines, and bacterial DNA.
What bacteria does sulfamethoxazole target?
Trimethoprim-sulfamethoxazole, a broad-spectrum synergistic combination, is still widely used to treat gram-negative bacterial infections, particularly those in the urinary tract. It has shown tremendous success in the prevention and treatment of Pneumocystis carinii pneumonia.
