Tramadol Impurities

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Parent Drug Name Name of Impurity Catalogue No.
Tramadol Tramadol 3-Methoxyphenol Impurity VL147010View
Tramadol Tramadol EP Impurity A (Free Base) VE006835View CAS 152538-36-8
Tramadol Tramadol EP Impurity A (HCl salt) VL147009View CAS 73806-49-2
Tramadol Tramadol EP Impurity B VL147001View CAS 66170-32-9
Tramadol Tramadol EP Impurity C VL147002View CAS 66170-31-8
Tramadol Tramadol EP Impurity C (Free Base) VE009269View CAS 192384-41-1
Tramadol Tramadol EP Impurity D VL147003View CAS 185453-02-5
Tramadol Tramadol EP Impurity D (Free Base) VE006834View CAS 144830-15-9
Tramadol Tramadol EP Impurity E (HCl salt) VL147004View CAS 42036-65-7
Tramadol Tramadol N-Oxide Impurity VE006329View CAS 147441-56-3

Tramadol Related Compound

Tramadol is an opioid narcotic drug that is licensed to treat moderate to moderately severe pain in people.

References

  • Tamanai-Shacoori, Zohreh, et al. “The Antibacterial Activity of Tramadol against Bacteria Associated with Infectious Complications after Local or Regional Anesthesia.” Anesthesia & Analgesia, vol. 105, no. 2, Aug. 2007, pp. 524–27, https://doi.org/10.1213/01.ane.0000267525.51017.b8. Accessed 8 Mar. 2023. ‌
  • “Tramadol.” Arthritis.ca, 2017, arthritis.ca/treatment/medication/medication-reference-guide/medications/tramadol#:~:text=tramadol%20used%20for%3F-,Tramadol%20is%20as%20an%20alternative%20treatment%20option%20for%20osteoarthritis%20(OA,conjunction%20with%20acetaminophen%20or%20NSAIDs. Accessed 8 Mar. 2023.
  • Grond, Stefan, and Armin Sablotzki. “Clinical Pharmacology of Tramadol.” Clinical Pharmacokinetics, vol. 43, no. 13, 2004, pp. 879–923, https://doi.org/10.2165/00003088-200443130-00004. Accessed 8 Mar. 2023. ‌

FAQ

Is tramadol used as an antibiotic?

Tramadol’s antibacterial characteristics may be effective in lowering the risk of bacterial infection during local or regional anesthesia.

Is tramadol effective for joint pain?

Tramadol is an effective therapy option for osteoarthritis (OA) of the knee and hip for those who have failed or are unable to use acetaminophen and nonsteroidal anti-inflammatory medicines (NSAIDs). Tramadol can also be used with acetaminophen or NSAIDs

What is the mechanism of action of tramadol?

(+)-Tramadol inhibits serotonin reuptake and (-)-Tramadol inhibits norepinephrine reuptake, hence increasing the inhibitory effects on pain transmission in the spinal cord. The complimentary and synergistic activities of the two enantiomers enhance the racemate’s analgesic effectiveness and tolerance profile.

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144830-15-9: Tramadol EP Impurity D (Free Base)

144830-15-9: Tramadol EP Impurity D (Free Base)
Catalogue No.

VE006834

CAS No.

144830-15-9

Molecular Formula

C15H23NO2

Molecular Weight

249.35

Parent drug

Tramadol

IUPAC Name

(1RS, 2RS)-2-[(Dimethylamino)methyl]-1-(3-hydroxyphenyl)cyclohexan-1-ol

Synonyms

O-Desmethyl Tramadol Impurity

References

Sci-Hub, Simultaneous Determination of Acetaminophen and Tramadol Impurities in combination product of Acetaminophen and Tramadol Tablets by UPLC with Trifunctional Octadecyl Column, 10.1080/22297928.2015.1128849. (2015). Retrieved January 29, 2022, from Sci-hub.ee website: https://sci-hub.ee/10.1080/22297928.2015.1128849 ?

Status

In-stock

ListName

Tramadol EP Impurity D (Free Base)

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