1-(2-metoxifenoxi)-3-(2-metoxifenilamino)propan-2-ol, C17H21NO4, com massa molecular de 303,35 g/mol, é um aminoálcool secundário que apresenta duas unidades éter anisílicas e um esqueleto hidroxipropílico quiral. A sua estrutura é compatível com uma impureza relacionada ao processo ou intermediário sintético originado por O-arilação ou N-alquilação incompletas, ou por rearranjos durante a fabricação multietapas de ariloxipropanolaminas relacionadas. Devido ao perfil polar e ionizável, a caracterização em nível de traço geralmente requer LC-MS/MS, com confirmação por LC-HRMS e técnicas ortogonais como HPLC-UV ou GC-MS após derivatização quando a volatilidade é necessária. A avaliação regulatória deve considerar a origem, o fator de resposta relativo e a possível transferência para o princípio ativo final.
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