Salbutamol Impurity D CRS (CAS 156339-88-7) é uma impureza bem caracterizada do salbutamol | quimicamente identificada como 5-(2-tert-butylamino-1-hydroxyethyl)-2-hydroxybenzaldehyde | também descrita como 5-[(1RS)-2-[(1 | 1-dimethylethyl)amino]-1-hydroxyethyl]-2-hydroxybenzaldehyde. Apresenta grupos aldeído e fenólico e um centro quiral racêmico | propriedades que influenciam solubilidade e comportamento analítico. É utilizada como padrão certificado para identificação e quantificação em estudos de estabilidade e controle de qualidade | mediante técnicas como HPLC-UV | LC-MS e RMN para confirmação estrutural. A monitorização desta impureza é crítica para conformidade com requisitos regulatórios de impurezas em ingredientes farmacêuticos ativos.
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