(2R)-2-[(4R)-2-Oxo-4-propilpirrolidin-1-il]butanamida, CAS 357337-00-9, é uma impureza de processo quiral derivada de lactama, com fórmula molecular C11H20N2O2 e massa molecular de 212,29 g/mol. A estrutura reúne uma pirrolidin-2-ona substituída ligada a um motivo butanamida, compatível com formação durante ciclização, alquilação ou resolução incompleta de intermediários relacionados, em vez de degradação oxidativa. Pela definição estereoquímica, a pureza enantiomérica pode ser relevante no desenvolvimento do método. A quantificação geralmente requer LC-MS/MS ou LC-MS de alta resolução, com confirmação ortogonal por RMN e, quando necessário, LC quiral para avaliação de impurezas isoméricas em um contexto de controle alinhado ao ICH M7.
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![(2R)-2-[(4R)-2-Oxo-4-propylpyrrolidin-1-yl]butanamide](https://veeprho.com/wp-content/uploads/2026/08/2R-2-4R-2-Oxo-4-propylpyrrolidin-1-ylbutanamide-357337-00-9-VE0010072-1241-sqr.png "(2R)-2-[(4R)-2-Oxo-4-propylpyrrolidin-1-yl]butanamide")
