A 5-Bromo Keto THF Impurity (CAS 915095-84-0) é uma impureza carbonílica halogenada derivada de tetrahidrofurano, associada tipicamente a arraste da rota sintética ou à degradação oxidativa de intermediários bromados. Com fórmula molecular C17H14BrClO3 e massa molecular de 381,7 g/mol, trata-se de uma espécie estruturalmente modificada, cujos substituintes de bromo e cloro aumentam a retenção cromatográfica e a complexidade espectrométrica de massas. Sua caracterização geralmente requer HPLC em fase reversa acoplada a LC-MS/MS, com confirmação por MS de alta resolução e, quando a volatilidade permite, GC-MS. Impurezas halogenadas desse tipo são avaliadas sob os referenciais ICH Q3A/Q3B e, quando aplicável, sob considerações de genotoxicidade.
Referências
“Empagliflozin: MedlinePlus Drug Information.†Medlineplus.gov, 2021, medlineplus.gov/druginfo/meds/a614043.html
Solicitar orçamento
"*" indica campos obrigatórios
Outros produtos relacionados às Empagliflozin impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
