Bupropion Impurity 2 (3 | 5-dicloropropiofenona | CAS 92821-92-6) é uma impureza orgânica observada na síntese do bupropion | caracterizada por substituição diclorada no anel fenílico. Apresenta fórmula molecular C9H8Cl2O e propriedades físico-químicas que podem afetar o perfil de pureza e estabilidade do lote. É detectada e quantificada rotineiramente por HPLC e GC-MS | exigindo limites analíticos definidos em especificações devido ao seu potencial impacto toxicológico e farmacêutico. Controles de processo | purificação por cromatografia e testes de identificação são recomendados para minimizar níveis residuais e assegurar conformidade com boas práticas de fabricação.
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