(2S)-(t-Butylamino)-3′-chloropropiophenone L-tartaric acid salt
Sinônimos
N/A
Descrição
A impureza Bupropion (S)-Isomer (CAS 324548-43-8) refere-se ao isômero enantiomérico residuante gerado por racemização parcial ou síntese e resolução quiral incompletas; como impureza enantiomérica | influencia diretamente a pureza óptica do lote e exige caracterização técnica detalhada. A deteção e quantificação habitualmente utilizam cromatografia líquida de alta eficiência em fase quiral com limites de deteção e quantificação definidos | complementada por espectrometria de massa | RMN e determinação de rotação óptica para confirmação estrutural. Controlo eficaz envolve otimização de rota sintética | parâmetros de purificação | procedimentos de amostragem e validação de métodos analíticos | além de especificações e estudos de estabilidade para mitigar formação durante armazenamento e processamento.
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