Impureza Moxifloxacin Related Compound G (Free Base) | CAS 268545-13-7 | é o isômero óptico do moxifloxacino na forma de base livre | também referida como ent-Moxifloxacin | (4aR | 7aR)-Moxifloxacin | Moxifloxacin (R | R)-Isomer ou d-Moxifloxacin. Esta impureza enantiomérica pode surgir durante etapas de síntese ou resolução e requer monitorização rigorosa por técnicas analíticas como HPLC quiral | LC-MS e RMN para caracterização estrutural e quantificação. A presença deste composto pode afetar o perfil de pureza e o controle de qualidade do princípio ativo. Avaliações de impurezas relacionadas devem seguir limites regulamentares aplicáveis e procedimentos de validação analítica.
Referências
Tulkens, Paul M., et al. Moxifloxacin Safety.†Drugs in R&D, vol. 12, no. 2, June 2012, pp. 71–100, https://doi.org/10.2165/11634300-000000000-00000.
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