A impureza (R)-2 | 3-Dihydroxy-5-(1-Hydroxy-2-(Methylamino)ethyl)benzenesulfonic acid caracteriza-se por grupos diol | sulfonato e uma amina metilada | conferindo polaridade elevada e solubilidade em meios aquosos | o que pode afetar o perfil de pureza e a estabilidade do produto final; sua ocorrência é associada a vias de degradação e reações secundárias durante a síntese e purificação. A identificação e quantificação requerem técnicas sensíveis como HPLC com detecção UV ou MS | LC-MS de alta resolução e RMN para confirmação estrutural. Recomenda-se estabelecer limites analíticos | procedimentos de amostragem e estratégias de remoção por cromatografia ou troca iônica para controle de qualidade e conformidade regulatória.
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