Services

Library of Chemical compounds

CUSTOM SYNTHESIS OF IMPURITIES

We have synthesized more than 10,000 impurities as of date. VEEPRHO can provide fast and reliable service for a custom synthesis of impurities, based on the following information:

1) Structure of the impurity.
2) Name of the parent drug.
3) Required quantity.
4) CAS No. of the impurity (if available)

Please contact us if you require custom synthesis and we would be glad to help you with our custom synthesis service.

IMPURITY ISOLATION AND PURIFICATION

Isolation and Purification of Known and Unknown Impurities from milligram to gram scale, which is performed by our talented team of scientists who always provide high-quality products. We have executed the most critical isolation and purification projects from the drug product, API, and structure elucidation of the appropriate project.

Structure Interpretation Studies for spatial heterogeneity identifications, we conduct these studies on reactants, products, or conditions by using 2-D NMR techniques. These studies involve homonuclear correlation experiments like NOESY, DQF-COSY, TOCSY, and ROESY and heteronuclear correlation experiments like HMQC, HSQC, and HMBC.

CERTIFIED IMPURITY STANDARDS

All VEEPRHO products are supplied with certificates of analysis (COA). We are a supplier and manufacturer of impurity standards. A standard certificate of analysis contains the following information:
1. Identification by 1H-NMR, and Mass spectroscopy.
2. Purity test by either HPLC or GC.
3. Additional characterization data such as 13C NMR, TGA, CHN, and IR will be provided on request.

Technical specifications of the standard data provided in COA are:

Quantification studies by NMR, MS/MS studies and mass accuracy up to 4th decimal -Q-TOF, for volatile or neutral molecules, less than 500 AMU GCMS.

Our lab is equipped with:
1. Vertis 25EL Lyophilizer.
2. Waters Prep HPLC with PDA.
3. Water and Thermo Fisher HPLC with PDA and UV.
4. LCMS.
5. UV Spectrophotometer-Shimadzu.
6. pH meter, and all equipment monitoring devices.

The Synthetic Chemistry team at Veeprho is well trained to design and synthesize novel compounds from milligram to gram quantity. Capacity to carry out multi-step synthesis using the latest technologies and methods.