Almotriptan Related Compound A / Almotriptan Hydroxymethyl Impurity
Beschreibung
Almotriptan Related Compound A or Almotriptan Hydroxymethyl Impurity (CAS No: 1018676-02-2) is an impurity formed during the synthesis of Almotriptan. Almotriptan hydrogen malate is a selective serotonin (5-HT)1B/1D agonist that belongs to the class of second-generation triptans, which is utilized for the acute treatment of the headache phase of migraine attacks.
References
Kumar, A. Phani, et al. “A Validated Reversed Phase HPLC Method for the Determination of Process-Related Impurities in Almotriptan Malate API.†Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 4, Mar. 2008, pp. 792–98, https://doi.org/10.1016/j.jpba.2007.11.029. ?Orlandini, S., et al. “An Integrated Quality by Design and Mixture-Process Variable Approach in the Development of a Capillary Electrophoresis Method for the Analysis of Almotriptan and Its Impurities.†Journal of Chroma
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