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Enthält: HPLC, MASS/LC-MS, 1H-NMR, FT-IR, Gehalt, Structure Elucidation Report (SER) sowie zusätzliche analytische Daten je nach Produkt.
182808-04-4Prucalopride Inhouse Impurity D
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| Katalog-Nr.:: | VE006181 |
|---|---|
| CAS-Nr.:: | 182808-04-4 |
| Summenformel:: | C10H10ClNO3 |
| Molare Masse:: | 227.64 g/mol |
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Zusätzliche Informationen zu CAS 182808-04-4
Parent drug
PrucaloprideIUPAC-Name
Methyl 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylateSynonyme
Prucalopride Related Compound 7Pharmacopeial Synonyms
N/ASMILES
O=C(C1=C(OCC2)C2=C(N)C(Cl)=C1)OCInChI
InChI=1S/C10H10ClNO3/c1-14-10(13)6-4-7(11)8(12)5-2-3-15-9(5)6/h4H,2-3,12H2,1H3Beschreibung
Prucalopride Impurity D (Prucalopride Related Compound 7, CAS 182808-04-4) is a process-related byproduct observed during prucalopride synthesis and stability studies. Characterization typically employs HPLC with UV detection, LC-MS for accurate mass confirmation, and NMR for structural assignment. This impurity can influence API purity, assay accuracy and stability profiles, therefore trace-level identification, quantification and qualification per ICH Q3A/B guidelines are essential. Control strategies include optimized reaction parameters, targeted purification steps and validated stability-indicating methods with defined acceptance criteria. Supply of well-characterized reference material supports method development, impurity profiling and regulatory submissions for pharmaceutical quality assurance.Angebot anfordern
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