103060-53-3Daptomycin Working Standard (Secondary Reference Standard)

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Catalogue No.:	VE0010034
CAS No.:	103060-53-3
Mol. Formula:	C72H101N17O26
Mol. Weight:	1620.67 g/mol

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Additional information on CAS 103060-53-3

Parent drug

Daptomycin

IUPAC Name

2,2′-((3S,6S,9R,15S,18R,21S,24S)-30-((S)-2-((S)-4-Amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((R)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontane-15,21-diyl)diacetic Acid

Synonyms

N/A

Pharmacopeial Synonyms

N/A

Smiles

O=C1NCC(N[C@@H](CCCN)C(N[C@@H](CC(O)=O)C(N[C@H](C)C(N[C@@H](CC(O)=O)C(NCC(N[C@H](CO)C(N[C@@H]([C@H](C)CC(O)=O)C(N[C@@H](CC(C2=CC=CC=C2N)=O)C(OC(C)C1NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CC3=CNC4=C3C=CC=C4)=O)CC(N)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

InChI

InChI=1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37?,43+,44+,45+,46+,47+,48+,49+,50-,60+,61?/m1/s1

Description

Daptomycin Working Standard (Secondary Reference Standard), CAS 103060-53-3, is a characterized secondary reference material provided for analytical laboratories and research organizations and is traceable to an applicable pharmacopeial reference standard such as USP, BP, JP, or Ph. Eur., as applicable. It is intended for research and analytical use. Supplied with a comprehensive certificate of analysis documenting identity by relevant analytical techniques such as mass, 1H NMR, and FT-IR, together with assay by HPLC and other applicable quality attributes such as loss on drying and residual solvents, this working standard is suitable for analytical laboratory use where consistent and well-documented secondary reference material is required.

References

Hamed, K., Gonzalez-Ruiz, A., & Seaton, A. (2016). Daptomycin: an evidence-based review of its role in the treatment of Gram-positive infections. Infection and Drug Resistance, 47. https://doi.org/10.2147/idr.s99046