16-Dehydro Pregnenolone Acetate Oxime (DHPG Oxime Acetate)
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2174-13-216-Dehydro Pregnenolone Acetate Oxime (DHPG Oxime Acetate)

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Catalogue No.:VL830003
CAS No.:2174-13-2
Mol. Formula:C23H33NO3
Mol. Weight:371.51 g/mol

Additional information on CAS 2174-13-2

Parent drug

Abiraterone

IUPAC Name

3β-Hydroxy-pregna-5,16-dien-20-one Acetate Oxime

Pharmacopoeial Synonyms

N/A

Other Synonyms

N/A

Smiles

CC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)C(/C(C)=N/O)=CC[C@@]4([H])[C@]3([H])CC=C2C1)=O

InChI

InChI=1S/C23H33NO3/c1-14(24-26)19-7-8-20-18-6-5-16-13-17(27-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,7,17-18,20-21,26H,6,8-13H2,1-4H3/b24-14+/t17-,18-,20-,21-,22-,23+/m0/s1

Description

The compound 16-Dehydro Pregnenolone Acetate Oxime (DHPG Oxime Acetate) is a thoroughly characterized reference standard that complies with rigorous regulatory guidelines, including those from USP, EMA, JP, and BP. It is ideal for critical applications such as analytical method development, method validation (AMV), and quality control (QC), especially in the production of Abiraterone. Designed to support both Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA), this product delivers the precision required for reliable results. Additionally, it includes a detailed Structure Elucidation Report (SER), ensuring accuracy and dependability for advanced analytical purposes. 16-Dehydro Pregnenolone Acetate DHPG Acetate (CAS No.: 2174-13-2) is used in the synthesis of biologically important steroids, 20-epi cholanic acid derivatives. Further, it is extensively used as a building block for the synthesis of a large number of steroidal drugs including anabolic steroids, corticosteroids, sex hormones, and contraceptives.

References

Shingate, Bapurao B., et al. “Stereoselective Syntheses of 20-Epi Cholanic Acid Derivatives from 16-Dehydropregnenolone Acetate.” Tetrahedron, vol. 63, no. 25, June 2007, pp. 5622–35, https://doi.org/10.1016/j.tet.2007.04.014.

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