Bicalutamide JP Related substance N (CAS No. 455-15-2)Â is an impurity present in Bicalutamide, Bicalutamide is an androgen receptor inhibitor, Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue, which is used to treat Stage d2 metastatic carcinoma of the prostate.
References
Neyman, A., Fuqua, J. S., & Eugster, E. A. (2019). Bicalutamide as an Androgen Blocker With Secondary Effect of Promoting Feminization in Male-to-Female Transgender Adolescents. Journal of Adolescent Health, 64(4), 544–546. https://doi.org/10.1016/j.jadohealth.2018.10.296
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