Bilastine-D6, CAS 1215358-58-9, is a stable isotopically labeled analogue of the H1-antihistamine bilastine, with formula C28H31D6N3O3 and molecular weight 469.65 g/mol. Replacement of six exchangeable hydrogen atoms with deuterium yields a mass-shifted internal standard used to distinguish analyte from structurally related impurities, degradants, and matrix interferences. As a labeled reference material, it is relevant in LC-MS/MS and high-resolution MS for exact-mass confirmation and isotope-dilution quantification. Its use supports characterization of synthetic route impurities and degradation products arising from oxidative or hydrolytic stress.
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