1-(4-Fluorphenyl)but-3-en-1-on, CAS 61668-02-8, ist ein aromatisches Enon-Keton mit der Summenformel C10H9FO und einer Molekülmasse von 164,17 g/mol. Die Struktur ist mit einem synthetischen Zwischenprodukt oder einem prozessbedingten Verunreinigungsprofil vereinbar, das aus unvollständiger Acylierung, Seitenketten-Olefinierung oder konkurrierender Bildung arylischer Ketone bei der Herstellung von Fluorphenyl-Derivaten entstehen kann. Die konjugierte Carbonylgruppe und die terminale Doppelbindung bewirken UV-Absorption und ermöglichen die empfindliche Charakterisierung mittels LC-MS/MS, GC-MS und 1H-NMR, wobei die chromatographische Trennung häufig eine RP-HPLC erfordert. Obwohl kein Nitrosamin, ist der Stoff im Rahmen der Verunreinigungsbewertung und routenspezifischer Kontrollkonzepte relevant.
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