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110104-37-5Acyclovir EP Impurity F

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Katalog-Nr.::	VL13007
CAS-Nr.::	110104-37-5
Summenformel::	C10H13N5O4
Molare Masse::	267.24 g/mol

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Zusätzliche Informationen zu CAS 110104-37-5

Parent drug

Acyclovir

IUPAC-Name

N-[6, 9-Dihydro-9-[(2-hydroxyethoxy)methyl]-6-oxo-1H-purin-2-yl]acetamide;

Pharmakopöe-Synonyme

Acyclovir Related Compound F

Other Synonyms

N2-Acetyl Acyclovir; N2-ACETYL-9-[(2′-HYDROXYETHOXY)METHYL]GUANINE; N-[9-(2-hydroxyethoxymethyl)-6-oxo-3H-purin-2-yl]acetamide; 9-((2-Hydroxyethoxy)methyl)-N2-acetylguanine; Acetamide, N-(6,9-dihydro-9-((2-hydroxyethoxy)methyl)-6-oxo-1H-purin-2-yl)-

SMILES

CC(=O)NC1=NC2=C(C(=O)N1)N=CN2COCCOC(=O)C

Beschreibung

Acyclovir EP Impurity F (CAS No: 110104-37-5) or N2-Acetyl Acyclovir/9-[(2-Hydroxyethoxy)methyl]-N2-acetylguanine is an impurity formed during the industrial production of acyclovir, which is a synthetic purine nucleoside analogue having inhibitory activity against the herpes simplex virus and varicella-zoster virus.

References

Huidobro, A. L., et al. â€œLC Methods for Acyclovir and Related Impurities Determination.â€ Journal of Pharmaceutical and Biomedical Analysis, vol. 37, no. 4, Apr. 2005, pp. 687â€“94, https://doi.org/10.1016/j.jpba.2004.11.039.