Alfacalcidol EP Impurity A (CAS No: 65445-14-9) or trans-Alfacalcidol is an impurity formed in Alfacalcidol that is a synthetic analog of Calcitriol, which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source.
References
Holick, M. F., et al. “1a-Hydroxy Derivative of Vitamin D 3 : A Highly Potent Analog of 1a, 25-Dihydroxyvitamin D 3.â€Â Science, vol. 180, no. 4082, Apr. 1973, pp. 190–91,  https://doi.org/10.1126/science.180.4082.190. de Nijs, Ron N. J., et al. “Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis.†New England Journal of Medicine, vol. 355, no. 7, Aug. 2006, pp. 675–84,  https://doi.org/10.1056/nejmoa053569.
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