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154229-20-6Anhydro Abiraterone

● Under Development

Katalog-Nr.::	VL830016
CAS-Nr.::	154229-20-6
Summenformel::	C24H29N
Molare Masse::	331.5 g/mol

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Zusätzliche Informationen zu CAS 154229-20-6

Parent drug

Abiraterone

IUPAC-Name

3-((8R, 9S, 10R, 13S, 14S)-10, 13-Dimethyl-2, 7, 8, 9, 10, 11, 12, 13, 14, 15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine

Pharmakopöe-Synonyme

N/A

Other Synonyms

N/A

SMILES

C[C@@]12C(C3=CC=CN=C3)=CC[C@@]1([H])[C@]4([H])CC=C5C=CCC[C@]5(C)[C@@]4([H])CC2

InChI

InChI=1S/C24H29N/c1-23-13-4-3-7-18(23)8-9-19-21-11-10-20(17-6-5-15-25-16-17)24(21,2)14-12-22(19)23/h3,5-8,10,15-16,19,21-22H,4,9,11-14H2,1-2H3/t19-,21-,22-,23-,24+/m0/s1

Beschreibung

The compound Anhydro Abiraterone is a thoroughly characterized reference standard that complies with rigorous regulatory guidelines, including those from USP, EMA, JP, and BP. It is ideal for critical applications such as analytical method development, method validation (AMV), and quality control (QC), especially in the production of Abiraterone. Designed to support both Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA), this product delivers the precision required for reliable results. Additionally, it includes a detailed Structure Elucidation Report (SER), ensuring accuracy and dependability for advanced analytical purposes. Anhydro Abiraterone (CAS No: 154229-20-6) is an impurity formed during the synthesis of Abiraterone acetate which is a derivative of steroidal progesterone. It is classified as an adrenal inhibitor, used for hormonal therapy for advanced prostate and breast cancer.

References

Kavitapu, DasameswaraRao, et al. â€œNew Stability Indicating RP-HPLC Method for the Determination of Abiraterone Acetate, Its Related Substances and Degradation Products in Bulk and Dosage Form.â€ Materials Today: Proceedings, vol. 34, 2021, pp. 469â€“78, https://doi.org/10.1016/j.matpr.2020.02.665. ?